ID A0A3B3SSP2_9TELE Unreviewed; 1286 AA.
AC A0A3B3SSP2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Euchromatic histone-lysine N-methyltransferase 1b {ECO:0000313|Ensembl:ENSPKIP00000033724.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000033724.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000033724.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR STRING; 1676925.ENSPKIP00000033724; -.
DR Ensembl; ENSPKIT00000014618.1; ENSPKIP00000033724.1; ENSPKIG00000013166.1.
DR GeneTree; ENSGT00940000156002; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0140938; F:histone H3 methyltransferase activity; IEA:UniProt.
DR GO; GO:0002039; F:p53 binding; IEA:InterPro.
DR GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd20905; EHMT_ZBD; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR043550; EHMT1/EHMT2.
DR InterPro; IPR047762; EHMT_CRR.
DR InterPro; IPR007728; Pre-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR46307; G9A, ISOFORM B; 1.
DR PANTHER; PTHR46307:SF2; HISTONE-LYSINE N-METHYLTRANSFERASE EHMT1; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF21533; EHMT1-2_CRR; 1.
DR Pfam; PF05033; Pre-SET; 1.
DR Pfam; PF00856; SET; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 6.
DR SMART; SM00468; PreSET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 5.
DR PROSITE; PS50088; ANK_REPEAT; 5.
DR PROSITE; PS50867; PRE_SET; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454}.
FT REPEAT 758..790
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 791..823
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 824..846
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 858..890
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 924..956
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 1046..1109
FT /note="Pre-SET"
FT /evidence="ECO:0000259|PROSITE:PS50867"
FT DOMAIN 1112..1229
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 61..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 297..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 629..684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1259..1286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..216
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 235..261
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..285
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 320..340
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..402
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1286 AA; 139905 MW; A31121678DEB11EF CRC64;
MEAIKGKPSG LAKAVLGRGD SMKTDVMKEP LCIKEGGNDD VAVDKKGHAL KNEKEVNGIC
ERLELGKGHQ SSGPHLPQDS KAGRQSECGP RARISENGLP ENEAPHGSVT GSNGFVLAKQ
QPEGGTPHRT SGSPIGGALV GHAAKTLPPS SARARNVGSV KTDGGAGMGV ATDGRAESET
KNGTSQDPPP VTIHRARKTM ARPASNQPTL KLLNRESQEP NGAKDETRSG LEAGKPPPAL
PPQPQLPQSQ SDAPAPPSKP QPATGVSRKK KRKMGTYSLV PKKKTKVLKQ RSVLDLFKDL
SRKAIQTQKG LRVNGESVEN ESEEESEEGE DSEEEDEQVG DEAGAVSREE PRTPDAALQV
GLLGEKAAGS SFEDCGPDQL VGEQESEESG DDEGEEEGND SDLSSESSLK KRMKKKMKGD
KPWLQTSRKR KRKKQLKAEG LPGNETEVQS QINTSKEYTE VPLVSLNLEV QEEFLVSQQS
GLPGGPGGVE TDLVQELPLC SCRMETPKSR EILTLANRKC MATESVDGQL SRCQSSVTKH
EMMRPSNTVQ LLVLCEDHRA GMVKHQCCPG CGFFCRAGTF MECQPDSNIS HRFHRACASV
LKGQTFCPHC GEDAGKAKEV TIAKADTTSM VPLSPGPKMP TVSEGKADTT TGGLAHVPRS
IDHRADSSLP RTPEMSDTQS PGSKAAVAMG LGVGSAPAPG PPKETLESVL LALDAEKPKK
LRFHPKQLYI SAKQGELQKV LLMLVDGIDP NYKMESQSKR TPLHVAAEAG HQEVCHLLVQ
AGANLDMCDD DQRTPLMDAC ENNHLETVRY LLRAGAIVSH KDVEGSTCLH LAAKIGHYDI
VQHLLDTCSI DINCQDDGGW TAVIWATEYK HVDQVKLLLS RGADINIRDK EENICLHWAA
FSGCVEIAEL LLGARCDLHA VNMHGDSPLH IAAREDRLDC VTLFLSRGAN VNLKNREGET
PLECCSHNSK VWSTLQTNRK LKEAAGTQAL QEEKVLNRDI ARGYEKVPVP CVNGVDAEPC
PDNYKYVPVN CVTSPMNIDK NITHLQYCVC KDDCSSTTCM CGQLSLRCWY DKEGRLLPEF
CREEPPLIFE CNHACSCWRT CKNRVVQNGL RMRLQLFRTA KTGWGVRALQ DVPQGTFVCE
YVGEIITDAE ADVRENDSYL FNLDNKVGDV YCIDARFYGN ISRFINHMCE PNLFPVRVFT
THQDLRFPHI AFFASKNISA GDEIGFDYGD HFWEIKGKQF SCQCGSLACR HSAAALAQRQ
ADSTPGGQQP SALPDTSSST TPSSPC
//
