ID A0A3B3STH4_9TELE Unreviewed; 375 AA.
AC A0A3B3STH4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Tumor necrosis factor receptor superfamily member 1B-like {ECO:0000313|Ensembl:ENSPKIP00000033630.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000033630.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000033630.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR STRING; 1676925.ENSPKIP00000033630; -.
DR Ensembl; ENSPKIT00000014522.1; ENSPKIP00000033630.1; ENSPKIG00000013275.1.
DR Ensembl; ENSPKIT00000014551.1; ENSPKIP00000033658.1; ENSPKIG00000013275.1.
DR GeneTree; ENSGT00940000166932; -.
DR OrthoDB; 5348767at2759; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR CDD; cd00185; TNFRSF; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 3.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR PANTHER; PTHR46875; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5; 1.
DR PANTHER; PTHR46875:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5; 1.
DR Pfam; PF00020; TNFR_c6; 2.
DR SMART; SM00208; TNFR; 4.
DR SUPFAM; SSF57586; TNF receptor-like; 3.
DR PROSITE; PS00652; TNFR_NGFR_1; 1.
DR PROSITE; PS50050; TNFR_NGFR_2; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00206};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..375
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040679958"
FT TRANSMEM 226..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 30..67
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 30..67
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT DOMAIN 69..110
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 69..110
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT REPEAT 111..153
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 111..153
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 155..196
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 155..196
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REGION 263..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 46..59
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 49..67
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 135..153
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 156..171
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 375 AA; 40589 MW; 10C81174A3723F2D CRC64;
MLRKILILWL AAFAQLNKVC ALPYQAEGTS CKNDNEYLNE ELNLCCSKCP PGKRLKVMCT
QGRDSDCQPC QPGTFSNKMN YANCHKCQSC RTDDNLVYIQ NCTSTTAAIC GCQEGWYCRS
VISTECKACS RYTSCPPGQG VSVKGAPTSN VKCKACDPGT YSDKHSYTKQ CQRHTDCTSQ
GKAVLHHGNS TADTVCEGAT RPVNSYSTPA RPAEPSQKPD GFKGSIFVIC GIIGTMLVLT
VIIIAITLAC RIKDGRNTDQ EVSKKFLPTK EKTRHPSFSS SSSQSESSHG VWVGPVSKEK
NKLNVSFTTT INLHQGASTQ AHLIPPLSAA AVSPGKLIKT DSNLSLSQEE MLDTFQKDEG
MEVPVAVQES GKAVC
//
