ID A0A3B3SVN6_9TELE Unreviewed; 372 AA.
AC A0A3B3SVN6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Serpin H1 {ECO:0000256|ARBA:ARBA00013551};
DE AltName: Full=Collagen-binding protein {ECO:0000256|ARBA:ARBA00030441};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000034822.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000034822.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Binds specifically to collagen. Could be involved as a
CC chaperone in the biosynthetic pathway of collagen.
CC {ECO:0000256|ARBA:ARBA00025405}.
CC -!- SIMILARITY: Belongs to the serpin family.
CC {ECO:0000256|ARBA:ARBA00009500, ECO:0000256|RuleBase:RU000411}.
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DR AlphaFoldDB; A0A3B3SVN6; -.
DR Ensembl; ENSPKIT00000015745.1; ENSPKIP00000034822.1; ENSPKIG00000013898.1.
DR GeneTree; ENSGT00940000156163; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 2.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 2.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR PANTHER; PTHR11461:SF27; SERPIN H1; 1.
DR Pfam; PF00079; Serpin; 2.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824}.
FT DOMAIN 31..363
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 372 AA; 42216 MW; B586BF7537DE478E CRC64;
MFCKRVIVCN TVVASPNKII EDNYKTKKYN LKLYHNMEND ASLKSENIFI SPVVLTSSLG
VITLGARQNT ANQVKSLLNV PLVEDSIHIL LSKLLTDASD EAISDIDWKV SSRSYGPAWI
NLSPDFVEKS EVHYRHNSSK VNFRDKWHHE NQQMDLPVID GALFINAMLL KPHWAEAFSH
KMVDKRGFMI SGTRTVSVQM MHRTDEPNQL QFLEIPLGKM QSSLLILMPF HMEPLEKVLT
KENIYRWSDQ LKEQAVAVSL PEADVGSIHE LQKYLKQLGL VEAVDKSKAD FSGITGKPDL
PLSHFLHAAG CEIQTGGNEF DENIFGREEL KTPKLFYADH PFIFFVQDTK TNSILFLGRL
LNPRNGGNHD EL
//
