ID A0A3B3SYC7_9TELE Unreviewed; 968 AA.
AC A0A3B3SYC7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=FERM domain containing 4A {ECO:0000313|Ensembl:ENSPKIP00000035654.1};
OS Paramormyrops kingsleyae.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000035654.1, ECO:0000313|Proteomes:UP000261540};
RN [1] {ECO:0000313|Ensembl:ENSPKIP00000035654.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3SYC7; -.
DR Ensembl; ENSPKIT00000016588.1; ENSPKIP00000035654.1; ENSPKIG00000014312.1.
DR GeneTree; ENSGT01020000230354; -.
DR Proteomes; UP000261540; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0090162; P:establishment of epithelial cell polarity; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13191; FERM_C_FRMD4A_FRMD4B; 1.
DR CDD; cd17199; FERM_F1_FRMD4A; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR021774; CUPID.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR047176; FRMD4A/B.
DR InterPro; IPR041785; FRMD4A/B_FERM_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46079; FERM DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR46079:SF3; FERM DOMAIN-CONTAINING PROTEIN 4A; 1.
DR Pfam; PF11819; CUPID; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
FT DOMAIN 5..307
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 350..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 544..641
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 655..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 750..806
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 909..968
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..575
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..641
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 765..784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 928..960
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 968 AA; 107494 MW; 9E0D41DF2F51792B CRC64;
MTEGRRCQVH LLDDRKLELL VQPKLMAKEL LDLVASHFNL KEKEYFGISY TDETGHFSWL
QLDRRVLEHE FPKKSGPVVL FFCVRFYIES ISYLKDNATI ELFFLNAKSC IYKELIDVDS
EVVFELASYI LQEAKGDFTS NEATRADLKK LPALPTQVLK EHPSLAYCED RVIEHYKKLG
GQSRGQAIVN YMSIVESLPT YGVHYYAVKD KQGIPWWLGL SYKGIFLYDY QDKVKPRKVF
QWRQLENLYF REKKFSVEVH DPRRASVSRR TFGHSGITVH TWYACPALIK SIWAMAISQH
QFYLDRKQSK SKIHVARSLS EIAIDLTETG TLKTSKLANM GSKGKIISGS SGSLLSSGSQ
ESDSSQTAKK DMLAALKARQ EALEETLRQR LEELRSICIR EAELTGKLPK EYPLDPGEDP
PTVRRKIGTA FKLDEQKILP RGEEEELERL EREFAIQSQI TEAARRLASD PHVTSKRLKK
QRKASYLNAL RKLQDIENAI NEYRVRSGKK PTQRASLIME EANIGSEDSS LSDALVLDDD
DLQVTGTFTP TASPHRSLPP RPPGHGRPPP PQSLDGLRHP HYQCGDYDKS PIKPKMWSES
SLDEPYERAK KRTSHIHSSS HRSLPSTGGC SEVGGSSPLQ RSPIRASLQW SLQSSLPSTP
NLRTRGPHCV QSTRSVDLSP TRLHSLAQHF RNRSSSLESQ SKLLDPESGC PDFCAPAAHG
SNGSDLPDDC SSCTSHSSSE HCYPAPGSAN YSTLAEDSPS KARQRHRSGG QLGSASSGSM
PNLAAQNGGG GGVGHRGVYL HSQSQPSSQY RIKEYPLYVE GGATPVVVRS LESDQEGHYS
VKAQFKTSSS YTAGGLYKEA WRGAEEASDG AGSRLTPSRS QIVRTPSLGR EGGARTAVSD
ELRCWYQRSS GSLKEHGSPR HSRPGSRMGT LGRSSPASPH SQRSVTLSSD STTTPPASPQ
HMVNWPGG
//
