ID   A0A3B3SYR7_9TELE        Unreviewed;       342 AA.
AC   A0A3B3SYR7;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Ion channel TACAN {ECO:0000256|ARBA:ARBA00039635};
DE   AltName: Full=Transmembrane protein 120A {ECO:0000256|ARBA:ARBA00041456};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000035784.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000035784.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}. Nucleus inner membrane
CC       {ECO:0000256|ARBA:ARBA00004473}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004473}.
CC   -!- SIMILARITY: Belongs to the TMEM120 family.
CC       {ECO:0000256|ARBA:ARBA00009700}.
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DR   AlphaFoldDB; A0A3B3SYR7; -.
DR   STRING; 1676925.ENSPKIP00000035784; -.
DR   Ensembl; ENSPKIT00000016721.1; ENSPKIP00000035784.1; ENSPKIG00000014564.1.
DR   GeneTree; ENSGT00390000007848; -.
DR   OrthoDB; 314124at2759; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR012926; TACAN/TMEM120B.
DR   PANTHER; PTHR21433:SF1; ION CHANNEL TACAN; 1.
DR   PANTHER; PTHR21433; TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA; 1.
DR   Pfam; PF07851; TMPIT; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        135..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        192..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        266..284
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        304..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   COILED          8..70
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   342 AA;  40795 MW;  A436A45DC5C830C8 CRC64;
     MLYSPTTIKE CLQEWEALEK DYQQVQETHR LYRQKLEEVS KLQDSCSAYI TRQKKKLKDL
     SASLEQCRET LSPEEVSAIE EIQDHIRERP NVFFEMESFL PKKNGLYLSL VLGNVNITLL
     NKQAKFAYKD EYEKFKLCLT VLLLLFSFTC RFVVTYRVVD ALFNFLLVWY YCTLTIRESI
     LISNGSRIKG WWVFHHYVST FLSGVMLTWP DGRLYQMFRN QFLTYSLYQS FVQFLQYYYQ
     SGCLYRLRAL GERHNMDLTV EGFQSWMWRG LTFLLPFLFF GHFWQLYNGL TLFRMAQLPE
     CKEWQVAMCG ASYLVLFMGN FFTTLGVVYH KYKHNRSKAK GL
//