ID   A0A3B3T170_9TELE        Unreviewed;       912 AA.
AC   A0A3B3T170;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Patched domain containing 4 {ECO:0000313|Ensembl:ENSPKIP00000036081.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000036081.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000036081.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the patched family.
CC       {ECO:0000256|ARBA:ARBA00005585}.
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DR   AlphaFoldDB; A0A3B3T170; -.
DR   STRING; 1676925.ENSPKIP00000036081; -.
DR   Ensembl; ENSPKIT00000017021.1; ENSPKIP00000036081.1; ENSPKIG00000014780.1.
DR   GeneTree; ENSGT00940000156827; -.
DR   OrthoDB; 2876883at2759; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR003392; Ptc/Disp.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR10796:SF15; PATCHED DOMAIN-CONTAINING PROTEIN 4; 1.
DR   PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR   Pfam; PF02460; Patched; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        43..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        289..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        321..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        350..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        391..412
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        424..451
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        520..541
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        715..738
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        744..764
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        817..835
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        847..868
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          299..450
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
FT   REGION          873..896
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   912 AA;  104122 MW;  46BCAB1940E87791 CRC64;
     MCFTGRNGAS ASWIWRRMLR QVIHRRLKAS FYWLGLFVSR HPVFFLTVPA VLTIIFGSTV
     LSRFKPEKNL EVLVAPTHSL AKIERSLANS LFPIDQSKNK LYSDLHTPGR YGRLILLAKS
     GANILELADQ VLQIHKKVLD MRVNYKGYNY TFAHLCVMRH RDKKCLLDDI ITIFEDIRSA
     ILSNSTLSKV PVSYPNTTLK DGRVSFIGHQ LGGVAFAPNS RDQQVKSARA VQITYYLHNY
     GSAAQDAIAE KWEHEFCQLV GRLSASRQDL RPQSLTSLSL WRDFHRTGML ARGEVLVGLV
     LVLLAATISS SMRDCLRGKP FLGLLGVLTI CIANVTAAGI FFISDGKFNS TLLGIPFFAM
     GHGTKGVFEL LAGWRRTREN LPFKERVADT FADVMVCYTM TSCLYIITFG MGASPFTNIE
     SVKIFCQSMC VAILVNYFYV FSFYGSCLVF AGQLEQNRYH SVFCCKIPSV EYLDKQPTWF
     KTMMSDGHDL SSHHDSIPYQ NHFIQHFLRE HYTEWITNTY VKPFVVILYL IYASFSFMGC
     LQISDGSNIV NLLVSNSPSV SYALTQQKYF SNYSPVIGFY IYEPIEYWNS TVQEHLKTLG
     HGFNKISWID NFFHYLKVVN VSASTKSEFI NILQTSFLRS PEYQHFKDDI IFSKTEDGIE
     IIASRMYLVA RTTEKTREEV VELLEKLRPL SLINSIKFIV FNPTFVFMDR YSSSIISPIL
     TSGFSVLTVL ILTFFLVINP LGNFWLILTI TSVELGVLGL MTLWNVDMDS ISILCLIYTL
     NFAMDHCAPH LYTFVLATEH TRTQCIKISL EEHGAAILQN TSCFVIGMMP LVFVPSNLTY
     TFFKCSLLTA GCTVLHCFVI LPVFLTFFPP SKKRHKKKKR AKRKERERER EREREEIECI
     EVRDNPDHVT NV
//