ID   A0A3B3T557_9TELE        Unreviewed;       320 AA.
AC   A0A3B3T557;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Thioredoxin related transmembrane protein 4 {ECO:0000313|Ensembl:ENSPKIP00000037800.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000037800.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000037800.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3T557; -.
DR   STRING; 1676925.ENSPKIP00000037800; -.
DR   Ensembl; ENSPKIT00000018776.1; ENSPKIP00000037800.1; ENSPKIG00000015835.1.
DR   GeneTree; ENSGT00940000160301; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR46107; DUMPY: SHORTER THAN WILD-TYPE; 1.
DR   PANTHER; PTHR46107:SF1; THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 4; 1.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        200..229
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          68..146
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|Pfam:PF00085"
FT   REGION          18..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          235..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        20..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        255..279
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        304..320
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   320 AA;  35757 MW;  8CCED2F83136E592 CRC64;
     MQSKGKAKYF KILLQGKHKN SASRPRNTSG CGWNTRSGTG GKWRIQSRVT RTWKKLHTAL
     DGNQTYNLPV VRHYAPWCPA CQQIKADWEE FGKRSEALGI SVGKVDVTQQ PGLSGRFLVT
     TLPTIFHAND GSFRRYLSSR AVEDFQSYVV DKKWEAVEPV PEWKSPSSFV MTMMSGLFRL
     SVWIRQIHSY LTETLGIPVW GSYLIFALVT LVTGLLLGLI LVLIADCICP SRPRRRDRKS
     EVEVKEDGSE GDIEDTLTEE RQLSDAENES AKLSGEEEST GEEVLPSEGE AGAADMQMPE
     GASESMVRKR KPQGAEPNET
//