ID   A0A3B3T6F7_9TELE        Unreviewed;       563 AA.
AC   A0A3B3T6F7;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Serine/threonine kinase 3 {ECO:0000313|Ensembl:ENSPKIP00000038742.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000038742.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000038742.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the NIPA family.
CC       {ECO:0000256|ARBA:ARBA00007230}.
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DR   AlphaFoldDB; A0A3B3T6F7; -.
DR   STRING; 1676925.ENSPKIP00000038742; -.
DR   Ensembl; ENSPKIT00000019736.1; ENSPKIP00000038742.1; ENSPKIG00000016383.1.
DR   GeneTree; ENSGT00940000154984; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0043010; P:camera-type eye development; IEA:Ensembl.
DR   CDD; cd06612; STKc_MST1_2; 1.
DR   Gene3D; 1.10.287.4270; -; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR008521; Mg_trans_NIPA.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   PANTHER; PTHR48015; SERINE/THREONINE-PROTEIN KINASE TAO; 1.
DR   PANTHER; PTHR48015:SF23; SERINE_THREONINE-PROTEIN KINASE 3; 1.
DR   Pfam; PF05653; Mg_trans_NIPA; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        439..461
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        482..504
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          26..277
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          300..342
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          370..389
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        326..342
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         55
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ   SEQUENCE   563 AA;  62652 MW;  B2F8CFA5C8E4B1E6 CRC64;
     MEPSAPKSKL KKLSEDSLTK QPEEVFDVLE KLGEGSYGSV YKAIHKESGQ VVAIKQVPVE
     SDLQEIIKEI SIMQQCDSPY VVKYYGSYFK NTDLWIVMEY CGAGSVSDII RLRNKTLTED
     EIATILKSTL KGLEYLHFMR KIHRDIKAGN ILLNTEGHAK LADFGVAGQL TDTMAKRNTV
     IGTPFWMAPE VIQEIGYNCV ADIWSLGITS IEMAEGKPPY ADIHPMRAIF MIPTNPPPTF
     RKPELWTDEF TDFVKKCLVK NPEQRATATQ LLQHPFIKNA KPVSILRDLI TEAMDIKAKR
     HQEQQRELEE DEENSEEEVE VDSHTMVKTS SESTGTMRAT GTMSDGAQTM IEHGSTMLDS
     DLGTMVINSD EEEEEDSTMK RNATSQQAQR PSFMDYFDKQ DPKGKAQENC NQNRPDSYHI
     AKNVFPDNWK VPQDGDFDFT YLIGIVIAIC GNFLISISLN IQKYTHMRQA QSGSKPYYTS
     SLWWCGIALM GIGELGNFAA YGFAPASLIA PLGCVSVIGK APPSVGHALL LHPVCCLFRA
     RSGSGGTVEL PQHLSHTNPS CAG
//