ID   A0A3B3TCD1_9TELE        Unreviewed;       191 AA.
AC   A0A3B3TCD1;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Copper transport protein {ECO:0000256|RuleBase:RU367022};
GN   Name=SLC31A1 {ECO:0000313|Ensembl:ENSPKIP00000040315.1};
OS   Paramormyrops kingsleyae.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Osteoglossocephala;
OC   Osteoglossomorpha; Osteoglossiformes; Mormyridae; Paramormyrops.
OX   NCBI_TaxID=1676925 {ECO:0000313|Ensembl:ENSPKIP00000040315.1, ECO:0000313|Proteomes:UP000261540};
RN   [1] {ECO:0000313|Ensembl:ENSPKIP00000040315.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Mobilizes copper(1+) out of the endosomal compartment, making
CC       copper(1+) available for export out of the cells.
CC       {ECO:0000256|ARBA:ARBA00037299}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Ag(+)(out) = Ag(+)(in); Xref=Rhea:RHEA:75207,
CC         ChEBI:CHEBI:49468; Evidence={ECO:0000256|ARBA:ARBA00036430};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Cu(+)(out) = Cu(+)(in); Xref=Rhea:RHEA:75211,
CC         ChEBI:CHEBI:49552; Evidence={ECO:0000256|ARBA:ARBA00036192};
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Early
CC       endosome membrane {ECO:0000256|ARBA:ARBA00004520}; Multi-pass membrane
CC       protein {ECO:0000256|ARBA:ARBA00004520}. Late endosome membrane
CC       {ECO:0000256|ARBA:ARBA00004107}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004107}. Membrane
CC       {ECO:0000256|RuleBase:RU367022}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU367022}.
CC   -!- SIMILARITY: Belongs to the copper transporter (Ctr) (TC 1.A.56) family.
CC       SLC31A subfamily. {ECO:0000256|RuleBase:RU367022}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3B3TCD1; -.
DR   Ensembl; ENSPKIT00000021334.1; ENSPKIP00000040315.1; ENSPKIG00000017329.1.
DR   GeneTree; ENSGT00940000155147; -.
DR   Proteomes; UP000261540; Unplaced.
DR   GO; GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005375; F:copper ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   InterPro; IPR007274; Cop_transporter.
DR   PANTHER; PTHR12483:SF22; HIGH AFFINITY COPPER UPTAKE PROTEIN 1; 1.
DR   PANTHER; PTHR12483; SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS; 1.
DR   Pfam; PF04145; Ctr; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Copper {ECO:0000256|RuleBase:RU367022};
KW   Copper transport {ECO:0000256|RuleBase:RU367022};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Ion transport {ECO:0000256|RuleBase:RU367022};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU367022};
KW   Oxidation {ECO:0000256|ARBA:ARBA00023097};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU367022};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU367022}; Transport {ECO:0000256|RuleBase:RU367022}.
FT   TRANSMEM        68..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367022"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367022"
FT   TRANSMEM        157..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU367022"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   191 AA;  20983 MW;  4BF268AD98CB54D3 CRC64;
     MSMSHDHSHH VHQGSMATMP PAVTGSHGGG HGEGGGGNHE MMMMQMTFYF DYRNVELLFS
     GLVINSPGGM VGACIVIFLM AVFYEGLKIG REYLLRRNQV SVRYNSMPVP GPDGTVLMET
     HKTVGQRMLS LAHLLQTALH IIQVVVSYFL MLVFMTFNGY LCIAVAAGAG VGYFLFSWKK
     AVVVDITEHC H
//