ID A0A3B3TIT1_9TELE Unreviewed; 405 AA.
AC A0A3B3TIT1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Fatty acid desaturase 2-like {ECO:0000313|Ensembl:ENSPLAP00000000483.1};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000000483.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000000483.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- PATHWAY: Lipid metabolism; polyunsaturated fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005105}.
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DR AlphaFoldDB; A0A3B3TIT1; -.
DR Ensembl; ENSPLAT00000016348.1; ENSPLAP00000000483.1; ENSPLAG00000003271.1.
DR GeneTree; ENSGT00950000182990; -.
DR UniPathway; UPA00658; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0006636; P:unsaturated fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd03506; Delta6-FADS-like; 1.
DR Gene3D; 3.10.120.10; Cytochrome b5-like heme/steroid binding domain; 1.
DR InterPro; IPR001199; Cyt_B5-like_heme/steroid-bd.
DR InterPro; IPR036400; Cyt_B5-like_heme/steroid_sf.
DR InterPro; IPR005804; FA_desaturase_dom.
DR InterPro; IPR012171; Fatty_acid_desaturase.
DR PANTHER; PTHR19353:SF12; ACYL-COA 6-DESATURASE; 1.
DR PANTHER; PTHR19353; FATTY ACID DESATURASE 2; 1.
DR Pfam; PF00173; Cyt-b5; 1.
DR Pfam; PF00487; FA_desaturase; 1.
DR PIRSF; PIRSF015921; FA_sphinglp_des; 2.
DR PRINTS; PR00363; CYTOCHROMEB5.
DR SMART; SM01117; Cyt-b5; 1.
DR SUPFAM; SSF55856; Cytochrome b5-like heme/steroid binding domain; 1.
DR PROSITE; PS50255; CYTOCHROME_B5_2; 1.
PE 4: Predicted;
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023160}.
FT DOMAIN 11..88
FT /note="Cytochrome b5 heme-binding"
FT /evidence="ECO:0000259|PROSITE:PS50255"
SQ SEQUENCE 405 AA; 47187 MW; 811F9EADC940FA81 CRC64;
MGVGGQQTEA ADVFSWEEVQ KHRSRNDRWL VISRKVYNIS QWAKRHPGGS HVIGHYAGED
ATEAFTAFHP DQKFVQKFLK PLLIGELAAT EPSQDGNKNK DGLFKALAWM MVWYWGTSWT
LTLLCAVMLA TSQAQAGWLQ HDFGHLSVFK KSKWNHLVHK FVIGHLKGAA ASWWNHLHYN
HHAKPNVLSK DPDVNMSGVF VLGSVQPVEY GMKKIKHMPY NHQHQYFFLL GPPLLVPVVF
NLQNLNVMIS RRNWVDLAWY LSFYIRYFSC YVPLYGVFGA VALNLFVRFL ESHWFVWVTQ
MNHLPMNIDH EKNRDWVTMQ LQATCNIEKS FFNDWFSGHL NFQIEHHLFP RMPRHNYHLV
APRVRALCDK HGISYQMKTL WRGMTDVVSS LKTSGDLWLD AYLHK
//
