ID   A0A3B3TQ99_9TELE        Unreviewed;       635 AA.
AC   A0A3B3TQ99;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Polyadenylate-binding protein {ECO:0000256|RuleBase:RU362004};
DE            Short=PABP {ECO:0000256|RuleBase:RU362004};
OS   Poecilia latipinna (sailfin molly).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000002773.1, ECO:0000313|Proteomes:UP000261500};
RN   [1] {ECO:0000313|Ensembl:ENSPLAP00000002773.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Binds the poly(A) tail of mRNA.
CC       {ECO:0000256|RuleBase:RU362004}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU362004}.
CC   -!- SIMILARITY: Belongs to the polyadenylate-binding protein type-1 family.
CC       {ECO:0000256|ARBA:ARBA00008557, ECO:0000256|RuleBase:RU362004}.
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DR   RefSeq; XP_014897217.1; XM_015041731.1.
DR   RefSeq; XP_014897218.1; XM_015041732.1.
DR   RefSeq; XP_014897220.1; XM_015041734.1.
DR   AlphaFoldDB; A0A3B3TQ99; -.
DR   STRING; 48699.ENSPLAP00000002773; -.
DR   Ensembl; ENSPLAT00000012479.1; ENSPLAP00000002773.1; ENSPLAG00000004114.1.
DR   GeneID; 106953159; -.
DR   KEGG; plai:106953159; -.
DR   CTD; 26986; -.
DR   GeneTree; ENSGT00940000160311; -.
DR   OrthoDB; 21912at2759; -.
DR   Proteomes; UP000261500; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   CDD; cd12378; RRM1_I_PABPs; 1.
DR   CDD; cd12379; RRM2_I_PABPs; 1.
DR   CDD; cd12380; RRM3_I_PABPs; 1.
DR   CDD; cd12381; RRM4_I_PABPs; 1.
DR   Gene3D; 3.30.70.330; -; 4.
DR   Gene3D; 1.10.1900.10; c-terminal domain of poly(a) binding protein; 1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR036053; PABP-dom.
DR   InterPro; IPR006515; PABP_1234.
DR   InterPro; IPR002004; PABP_HYD.
DR   InterPro; IPR034364; PABP_RRM1.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR045305; RRM2_I_PABPs.
DR   InterPro; IPR000504; RRM_dom.
DR   InterPro; IPR003954; RRM_dom_euk.
DR   NCBIfam; TIGR01628; PABP-1234; 1.
DR   PANTHER; PTHR24012:SF409; POLYADENYLATE-BINDING PROTEIN 1; 1.
DR   PANTHER; PTHR24012; RNA BINDING PROTEIN; 1.
DR   Pfam; PF00658; PABP; 1.
DR   Pfam; PF00076; RRM_1; 4.
DR   SMART; SM00517; PolyA; 1.
DR   SMART; SM00360; RRM; 4.
DR   SMART; SM00361; RRM_1; 3.
DR   SUPFAM; SSF63570; PABC (PABP) domain; 1.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 2.
DR   PROSITE; PS51309; PABC; 1.
DR   PROSITE; PS50102; RRM; 4.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|RuleBase:RU362004};
KW   mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176,
KW   ECO:0000256|RuleBase:RU362004}.
FT   DOMAIN          11..89
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          99..175
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          191..268
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          294..370
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
FT   DOMAIN          542..619
FT                   /note="PABC"
FT                   /evidence="ECO:0000259|PROSITE:PS51309"
SQ   SEQUENCE   635 AA;  71005 MW;  3027A0CFED29F2FD CRC64;
     MNPSAPSYPM ASLYVGDLHP DVTEAMLYEK FSPAGPILSI RVCRDMITRR SLGYAYVNFQ
     QPADAERALD TMNFDVIKGR PLRIMWSQRD PSLRKSGVGN IFIKNLDKSI DNKALYDTFS
     AFGNILSCKV VCDENGSKGY GFVHFETHEA AERAIEKMNG MLLNDRKVFV GRFKSRKERE
     AELGARAREF TNVYIKNFGE DMDDEKLKEL FSKYGPALSI RVMTDESGKS KGFGFVSFER
     HEDAQKAVDD MNGKELNGRQ VYVGRAQKKG ERQNELKRKF EQMKQDRMTR YQGVNLYVKN
     LDDGLDDERL RKEFSPFGTI TSAKVMMEGG RSKGFGFVCF SSPEEATKAV TEMNGRIVAT
     KPLYVALAQR KEERQAHLTN QYMQRMATVR AVPNPVLNPY QPAPPSGYFM AAIPQAQNRA
     AYYSANQLAQ LRPSPRWAAQ GVRPQHFQNM PNAMRPSAPR PQTFNTIRAT TTTNTQVPRM
     MASQRMPTQA LGQRPASASA TAAPVRTMPQ YKYAAGVRNP QQHMASQPQV AMQQPAVHVQ
     GQEPLTASML AAAPPQEQKQ MLGERLFPLI QNMHPSLAGK ITGMLLEIDN SELLHMLESP
     ESLRSKVDEA VAVLQAHQAK EAAQKSTTPA GVPSV
//