ID A0A3B3TTI4_9TELE Unreviewed; 735 AA.
AC A0A3B3TTI4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Leucine-rich repeat neuronal protein 2-like {ECO:0000313|Ensembl:ENSPLAP00000003902.1};
GN Name=LRRN2 {ECO:0000313|Ensembl:ENSPLAP00000003902.1};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000003902.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000003902.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR STRING; 48699.ENSPLAP00000003968; -.
DR Ensembl; ENSPLAT00000010453.1; ENSPLAP00000003968.1; ENSPLAG00000005570.1.
DR Ensembl; ENSPLAT00000010553.1; ENSPLAP00000003902.1; ENSPLAG00000005494.1.
DR GeneTree; ENSGT00940000161204; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR PANTHER; PTHR24373:SF394; LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS PROTEIN SMA-10; 1.
DR PANTHER; PTHR24373; SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN; 1.
DR Pfam; PF07679; I-set; 1.
DR Pfam; PF13855; LRR_8; 3.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SMART; SM00369; LRR_TYP; 11.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..735
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5040590382"
FT DOMAIN 433..523
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 626..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 626..643
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 735 AA; 81673 MW; DC8BABF3C6B430F2 CRC64;
MRPALALLQS HCLLYVFSGM CVPIVVGSLP PALPWYVPCP VRCVCQIKPW FSPDSVYHEA
PTVDCNNLLL TKLPLPIPLN THTLRLQSNL LSVLDTAVLH GLPNLTDLDL SQNRFSRVRM
ITQSSSLPSL LSIHLEENHL SHLPEASFSS LPALQELFLS HNNLHSIAPG AFNGLDSLRR
LHINNNRLTT IDPQWFRALP QLEVLMLGGN PVEALPERGF VALTSLRSLV LGGMGLRSLA
EKALEGLEEL ESLSFYDNHL TKVPRQALKR VPGLKFLDLN KNRIKLIETG DFKDMLNLKE
LGLNNMEELV SIDKASLDNL PELTKLEITN NPRLSYVHPQ AFVRLSRLES LMLNSNSLSA
LHQNIMLSLP SLQEVSLHSN PLRCDCLFHW AAQVARVVRF IQPEATLCSA PPELRARRVR
EVSSGEMSAS CLPTIPTSSL PSYVGVQEGG KLVLHCRALA EPYPELYWVT PSGLRLGPSF
FKHYQLQPEG TLEISRISPR EAGLYTCVAE NALGADTHSV TVGVHNRGKN RKRGVMTKPK
KFQSMRVEAR LELNEVGEHY AILSWQSRQN LPSTRLSWQA MQTSSHTPTY TTRILAGTQS
FNLTHLQAET FYRVCLHLGV SEDGKRDNLG SEGSKKPRCV SFRTKDVPEP QPGLQLNPEL
TSIAVTLLLL AYILLLAVQG WDLPNFPSIR TGSQDLNLAL CKGKKYKMLK CPGRTPSVTP
RPLEMSTSVS SALQG
//
