ID A0A3B3TTI9_9TELE Unreviewed; 760 AA.
AC A0A3B3TTI9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Transcription factor RFX3 {ECO:0000256|ARBA:ARBA00040859};
DE AltName: Full=Regulatory factor X 3 {ECO:0000256|ARBA:ARBA00042137};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000003604.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000003604.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_014882958.1; XM_015027472.1.
DR AlphaFoldDB; A0A3B3TTI9; -.
DR STRING; 48699.ENSPLAP00000003604; -.
DR Ensembl; ENSPLAT00000011062.1; ENSPLAP00000003604.1; ENSPLAG00000005171.1.
DR GeneID; 106944307; -.
DR KEGG; plai:106944307; -.
DR CTD; 5991; -.
DR GeneTree; ENSGT01050000244879; -.
DR OrthoDB; 2915941at2759; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003150; DNA-bd_RFX.
DR InterPro; IPR039779; RFX-like.
DR InterPro; IPR007668; RFX1_trans_act.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12619; RFX TRANSCRIPTION FACTOR FAMILY; 1.
DR PANTHER; PTHR12619:SF20; TRANSCRIPTION FACTOR RFX3; 1.
DR Pfam; PF04589; RFX1_trans_act; 1.
DR Pfam; PF02257; RFX_DNA_binding; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51526; RFX_DBD; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 178..253
FT /note="RFX-type winged-helix"
FT /evidence="ECO:0000259|PROSITE:PS51526"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 279..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 668..694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 741..760
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 760 AA; 84464 MW; C7646489DC4E7F0E CRC64;
MQTPEAGADS TSTVPLQTTV PVQPTSSTQQ VPVQQQQAQT VQQVQHVYPA QVQYVEENSG
VYTNGNIRTY TYSEPQLYSQ NSGGSYFDTQ GSSSQVSTVV TSHGMTNNGG GSTGGMSMGM
AGGQVISSSS GAYLMDNAGP HPATQTARAS PATIEMAIET LQKSEGLSSQ RSSLLNSHLQ
WLLDNYETAE GVSLPRSTLY NHYLRHCQEQ KLDPVNAASF GKLIRSIFMG LRTRRLGTRG
NSKYHYYGIR VKPDSPLNRL QEDMQYMALR QQPVQQKQRF KPVQKFDSGS GDNYTSGGQH
HPGAAEQTVI AQSQHHQQFL DASRALPDFI ELDLGQSSME NISPEDVKAL QSLYREHCEA
ILDVVVNLQF SLIEKLWQTF WRYSPPDTVE GATVTENSSI SEIEARLPRA QLLALCRNEA
VLKWMSTCDH LMYQALVEIL IPDVLRPIPS ALTQAIRNFA KSLEGWLSNA MNAIPQRMIQ
TKIAAVSAFA QTLRRYTSLN HLAQAARAVL QNTSQINQML SDLNRVDFAN VQEQASWVCQ
CEEGVVQHLE QDFKATLQQQ SSLEQWAAWL DNVVTQVLKP YEHRPSFPRA ARQFLLKWSF
YSSMVIRDLT LRSAASFGSF HLIRLLYDEY MFYLVEHRVA QATGETPIGV MGEFDNLHTL
SLASIDKDET SGMDSDLEED TEDSGEPLAK REKPEHEVIQ VIQVGALEDG SHPVVGVVQH
SVLHSLQQPL QDHTEHILTP SAGTPTIRHC STTGNTYASV
//
