ID   A0A3B3TVQ3_9TELE        Unreviewed;       749 AA.
AC   A0A3B3TVQ3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=L3MBTL histone methyl-lysine binding protein 3 {ECO:0000313|Ensembl:ENSPLAP00000005285.1};
OS   Poecilia latipinna (sailfin molly).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000005285.1, ECO:0000313|Proteomes:UP000261500};
RN   [1] {ECO:0000313|Ensembl:ENSPLAP00000005285.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3B3TVQ3; -.
DR   Ensembl; ENSPLAT00000008197.1; ENSPLAP00000005285.1; ENSPLAG00000007299.1.
DR   GeneTree; ENSGT00940000158264; -.
DR   Proteomes; UP000261500; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd20103; MBT_L3MBTL1-like_rpt3; 1.
DR   Gene3D; 2.30.30.140; -; 3.
DR   Gene3D; 4.10.320.30; -; 1.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR004092; Mbt.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR002515; Znf_C2H2C.
DR   InterPro; IPR036060; Znf_C2H2C_sf.
DR   PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR   PANTHER; PTHR12247:SF130; SAM DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02820; MBT; 3.
DR   Pfam; PF01530; zf-C2HC; 1.
DR   SMART; SM00561; MBT; 3.
DR   SUPFAM; SSF103637; CCHHC domain; 1.
DR   SUPFAM; SSF63748; Tudor/PWWP/MBT; 3.
DR   PROSITE; PS51079; MBT; 3.
DR   PROSITE; PS51802; ZF_CCHHC; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU01143}.
FT   REPEAT          217..317
FT                   /note="MBT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT   REPEAT          325..424
FT                   /note="MBT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT   REPEAT          433..528
FT                   /note="MBT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT   REGION          56..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          138..205
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          580..629
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..106
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        606..621
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   749 AA;  82644 MW;  A02EDF5CF5DB7A21 CRC64;
     MTDTPPSDGP SQGAEFDMMG ALDWKDGIAT LPGSDIRFRM TEFGTLEIVT DVEVKGQEAE
     ANRETLNPVP SHTPTPPPEV QSQASTATAP VNQSKPGSSQ AKAASGTDPG PNGELLRCRS
     CGGPVSRNAL IEGKYCSSCV QPSSGRSSPA EARDSQAVEG ERLGKRVRKK RKIYMDSGDE
     EEDNQEEPEE KAKSTKGRRG AKMAKLVPAT PNKKRAWSWP AYLEEGRTIA APVKLFKEHQ
     SFPQSRNSFK VGMKLEGLDP SHPSLFCVLT VAEIQGYRVR LHFDGYPECY DFWANADSWD
     LKPAGWCEKN GHKLLLPKGC KEGEFNWSTY VKNCRGQLAP KHLFKSLNTS VTPSGFRAGM
     KLEAADRKNP SQICVATIAA VVDNRLLIHF DSLDDTHDYW CDASSPYIHP VGFCEEAQLT
     LITPPEHKDP KNFSWEKYME EAGAQPAPAR AFKPRPPHGF QVGMKVEAVD KRNPMLIRVA
     TIVNTEDHRL KVHFDGWNMD YDYWVETDCP DLHPVGWCQK TGHPLQHPNS TSDSLPAPGQ
     GCPTPGCNGV GHIRGPRYGT HYTLVSCPYS EMNLNKEGLL PDRLGGERPL VLSGPPARGR
     RPDAHPNNPA QTTSAPAQSE PPLDPQSRMA PLPKYLKMHY VKDEIKTISL QQALHESVFP
     PGISASPPHR VALCWDKHCQ LLPEVLGLTA KRVATWSTEE VRHACTLWGG KKAFLLLTQA
     DIVKILSIKL GPALKIYNSI LMLKNADEE
//