ID   A0A3B3U108_9TELE        Unreviewed;       880 AA.
AC   A0A3B3U108;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Leptin receptor-like {ECO:0000313|Ensembl:ENSPLAP00000006613.1};
OS   Poecilia latipinna (sailfin molly).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000006613.1, ECO:0000313|Proteomes:UP000261500};
RN   [1] {ECO:0000313|Ensembl:ENSPLAP00000006613.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3U108; -.
DR   Ensembl; ENSPLAT00000005964.1; ENSPLAP00000006613.1; ENSPLAG00000009365.1.
DR   GeneTree; ENSGT00730000111209; -.
DR   Proteomes; UP000261500; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR   InterPro; IPR003961; FN3_dom.
DR   InterPro; IPR036116; FN3_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR041182; LEP-R_IGD.
DR   PANTHER; PTHR23037; CYTOKINE RECEPTOR; 1.
DR   PANTHER; PTHR23037:SF41; CYTOKINE RECEPTOR-LIKE FACTOR 2-RELATED; 1.
DR   Pfam; PF18589; ObR_Ig; 1.
DR   SUPFAM; SSF49265; Fibronectin type III; 1.
DR   PROSITE; PS50853; FN3; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        541..562
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          243..336
FT                   /note="Fibronectin type-III"
FT                   /evidence="ECO:0000259|PROSITE:PS50853"
FT   REGION          712..793
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        717..733
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        734..752
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        762..778
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   880 AA;  99538 MW;  BBBE5E3D840348CE CRC64;
     KHSTPCIIDL SWHLYLCCIN VAVSHFQGKI SCIKSLKYIS HVSLCAEVSY IPQMVVARAG
     DNVTVYCVLN GQSANANTAM WSLNRRVPLD PSLYHPVNQR VSQITFTASE TGLSDLLTCT
     QEWNIPYSKI YVEGGFISIT CVTNGDIDTM TCRWENKEWE IVKFRSKSAE MSCDEMEERV
     RGGEDVGEMG HECMPIKTTE KVCTFHPLKM NCYKLWLELH TRLGVIRCKP VYVSPINHVK
     PHPPTDVTAV SRSGGILRVT WKQPSLPVEG LQCQFRYYLL DVLEKWKFEK PVWVTWAEVE
     VPDMCQIYVV QVRCMHTSGI GYWSEWSESV HSTAQNSRAP ERGPDFWRIR QDDPDRNQSN
     ITLLFESFSA NWNTYCVDGF IVQHQASNGS VLRRQIDMVS SYSFEWNQEL HIVTVEAYNS
     LGSSVNNVNM TLEKQPKRRC LHSFYVLVIN STCVSLSWSL LHISSAPLFM VVQWFPRKQQ
     DFEDFGLSKK TWAKLSYTEP PTQLRGDFFS SEEYAFHLYP VFADGEGEPV VTIVKTGNPP
     AYMMLMFISL LCIAVFVTLV LSQNQMKKFV WKDVPNPNKC SWAKGVDFKT IDGFEYLFRP
     PEGLQASPLP PEKISKVTVV NKTLTKAFVQ TPTLLAPPSV VASTNSFLPC LNPRTGQLLE
     CEMALGGDTS PDPLTTSDIT INKLQPANAL VEQSSATTNS SAQSSVTYSK VLHTDTNPDH
     PPLHLHYKEG SRSSYSDEGN FSANNSDTSE TFPGGLWEVD SYHGTESDDP RRSYSYNSEK
     ELSEVSEQED DLDVGQKKAL HYLDIGHPPE DEENEEEESQ TELLKSAHLI REDCSAELYP
     LLNPDDSTDP KTLVQVSTCS FSSLYMPQYR KPDVNHIPHT
//