ID   A0A3B3U3W3_9TELE        Unreviewed;       658 AA.
AC   A0A3B3U3W3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   RecName: Full=Amyloid beta A4 precursor protein-binding family B member 1-interacting protein {ECO:0000256|ARBA:ARBA00040699};
DE   AltName: Full=APBB1-interacting protein 1 {ECO:0000256|ARBA:ARBA00042746};
OS   Poecilia latipinna (sailfin molly).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000008120.1, ECO:0000313|Proteomes:UP000261500};
RN   [1] {ECO:0000313|Ensembl:ENSPLAP00000008120.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the MRL family. {ECO:0000256|ARBA:ARBA00038382}.
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DR   RefSeq; XP_014893959.1; XM_015038473.1.
DR   RefSeq; XP_014893969.1; XM_015038483.1.
DR   RefSeq; XP_014893975.1; XM_015038489.1.
DR   AlphaFoldDB; A0A3B3U3W3; -.
DR   STRING; 48699.ENSPLAP00000008120; -.
DR   Ensembl; ENSPLAT00000003423.1; ENSPLAP00000008120.1; ENSPLAG00000010596.1.
DR   GeneID; 106951136; -.
DR   KEGG; plai:106951136; -.
DR   CTD; 54518; -.
DR   GeneTree; ENSGT00940000156105; -.
DR   OrthoDB; 3144731at2759; -.
DR   Proteomes; UP000261500; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01259; PH_APBB1IP; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR039664; GRB/APBB1IP.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR039665; PH_APBB1IP.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR11243:SF14; AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B MEMBER 1-INTERACTING PROTEIN; 1.
DR   PANTHER; PTHR11243; GROWTH FACTOR RECEPTOR-BOUND PROTEIN; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00788; RA; 1.
DR   PRINTS; PR01217; PRICHEXTENSN.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00314; RA; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50200; RA; 1.
PE   3: Inferred from homology;
FT   DOMAIN          170..256
FT                   /note="Ras-associating"
FT                   /evidence="ECO:0000259|PROSITE:PS50200"
FT   DOMAIN          300..409
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          19..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          84..142
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          430..658
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        105..142
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        430..460
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        462..562
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        571..612
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   658 AA;  71690 MW;  35B8348B0E9878AD CRC64;
     MDDIDAMFSD LLGEMDLLTQ SLGQETEPPE PLPSTGQEIN FSVGFTGLNA SIQDLEDNDL
     DALMADLVAD LSETEKKLEA EIQGLNAPPS SSSDLPPPPK GLGVQPASSI TSPPSPGNNR
     SSSVTTPSSS TSSPLPLPQS SKPTMEEIEA QMKADKIKLA LEKLKEAKVK KLVVKVVMND
     GSSKTLMVDE RQTVREVLDN LFEKTHCDCN VDWSLCETNH ELQLERTFED HENLVEPLLA
     WTRDSENKVL FQERKDKFEV FKNPQNFYLW KKDKKTLKDM KDKDKELLVQ ENFCGTSIIV
     PDLEGVLHLK EDGKKSWKQR LFQLRASGIY YVPKGKTKSS RDLICFVQFD NVNVYYGKDV
     KNRYKAPTDF CFVLKHPQIQ KESQYIKYLC CDDAWTMNLW VTGIRIAKYG ASLHENFKTA
     ERKAAVSAAV WTNRSTPSSS SPSTPSPTIR AKTATQANGH APKPQPGPPH QGIGNLPAPP
     PLNEILPPPP PEPVLPPPPP SLASKPPLSN FPPPPLSMDG LPPPPPPPPM DNFSEDPPDF
     LPPPPPPTSY SSLPPPPAPA PAANFGGNIN KSLPPPPPNP EFLPPPPPDP VFVASGAPPP
     PPPPPPPAAV SAPRPAAQQK KMPPAPPKRT TPTLQGGGGG GGDFMSELMS AMRKRTDQ
//