ID A0A3B3U5W0_9TELE Unreviewed; 808 AA.
AC A0A3B3U5W0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Dystrophin related protein 2 {ECO:0000313|Ensembl:ENSPLAP00000008293.1};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000008293.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000008293.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3U5W0; -.
DR Ensembl; ENSPLAT00000003141.1; ENSPLAP00000008293.1; ENSPLAG00000010873.1.
DR GeneTree; ENSGT00940000153467; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd16248; EFh_DRP-2; 1.
DR CDD; cd00176; SPEC; 1.
DR CDD; cd00201; WW; 1.
DR CDD; cd02334; ZZ_dystrophin; 1.
DR Gene3D; 1.20.58.60; -; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR015153; EF-hand_dom_typ1.
DR InterPro; IPR015154; EF-hand_dom_typ2.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR12268:SF16; DYSTROPHIN-RELATED PROTEIN 2; 1.
DR PANTHER; PTHR12268; E3 UBIQUITIN-PROTEIN LIGASE KCMF1; 1.
DR Pfam; PF09068; EF-hand_2; 1.
DR Pfam; PF09069; EF-hand_3; 1.
DR Pfam; PF00435; Spectrin; 1.
DR Pfam; PF00397; WW; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00150; SPEC; 1.
DR SMART; SM00456; WW; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF47473; EF-hand; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT DOMAIN 204..237
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 457..513
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT REGION 735..786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 628..662
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 704..734
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 740..763
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 764..785
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 808 AA; 91997 MW; 4ED5A9B546588FE5 CRC64;
MEDVKSRGPF IYSVLESAQA FLAQHPFQEP EETLTDGKEV SPRRRILNVS RSVWKQANVA
SDLWEKLTAR CVDRHRHMER TLECLLQIQA AMDELAGALE QAEGVRDAWE PVGDLFIDSL
QDHIDATKLF KEELSQVKEG MKQVNELAHQ LAISDVHLSM ENARVLEHLN SRWKVLQGSI
EERLKQLQDA HRDFGPGSQH FLSSSVQVPW ERAISPNKVP YYINHQAQTT CWDHPKMTEL
YQALADLNNI KFSAYRTAMK LRRVQKSLRL DLVALSSLVD VFREQELQQG EHVMDVVEVI
HGLTAVYEGL EEQRSLLVNI PLCVDMCLNW LLNVYDSARN GKMRVLSFKM GLVSLCNADV
QEKYKYLFRQ VSGPGGLTDQ RHLSLLLHEA IQIPRQLGEV AAFGGSNTEP SVRSCFRMAP
EKPAIEVSHF LEWMSLEPQS MVWLPVLHRV AAAESTKHQA KCYVCKQCPI KGFRYRSLKQ
FNVDICQTCF LTGRTSKGKK LHYPIMEYYT PTTSGEKMRD FAKTLKNKFR SKQYFTKHPQ
RGYLPVQSVL EAESSETPCS SPRLPHADTH SRIEHYASRL AEMENQNCSF FTDSLSPDES
LDEDQYLLRH SSPALDHDSP CGQHMLLAHL EHQDKEQLQC TLARLENENR VLQSEYRRLK
WKHEEAAALP MLTEAGEGGP GSPTAGGAQD EELLAEARVL RQHKTRLETR MQILEDHNKQ
LESQLRRLRE LLLQPKDDSE ANGSELSTLS SPVSGGGRQG EPPSRETTDT EAAGDDLERE
QDTVLQLQEV IEQLRNVFPS EPGTTSHI
//
