ID   A0A3B3U5W7_9TELE        Unreviewed;       883 AA.
AC   A0A3B3U5W7;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
OS   Poecilia latipinna (sailfin molly).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000008298.1, ECO:0000313|Proteomes:UP000261500};
RN   [1] {ECO:0000313|Ensembl:ENSPLAP00000008298.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3U5W7; -.
DR   STRING; 48699.ENSPLAP00000008298; -.
DR   Ensembl; ENSPLAT00000003124.1; ENSPLAP00000008298.1; ENSPLAG00000010835.1.
DR   GeneTree; ENSGT01070000253760; -.
DR   Proteomes; UP000261500; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF151; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12-RELATED; 1.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 3.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM00368; LRR_RI; 6.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
FT   DOMAIN          138..272
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   883 AA;  100133 MW;  B33569AD2ECE6F9F CRC64;
     MFWSCLLHRA TNAQRDSQNG GALLLKHLLC KKKKKISIPF CFCLSPGFSL QEDLDKHRNQ
     LRRRCKYITE GADELGARTV LNSIYTELYI TEGWSKEVNT QHEVKQLERA SKIQNLHDSP
     IRCHDIFKSF PDQHGAIRVV LTNGVAGVGK TFSVQKFTLD WAEGLENQDV SVVVLLSFRE
     LNLIRDEQHS LLSLLHVFHP TLQKLPAEQL AKCKLLFIFD GLDESRLSLD FNNSQLVSDV
     TQKSSVNVLL TNLIKGNLLP SALIWITTRP AAANQIPPSC VTRVTEVRGF TDAQKEEYFR
     RRFSDEELSS RIISHIKKSK TLHIMCGIPV FCWITATVLE NMLTSEQRGE LPKTMTDMYS
     HFLLVQTKRK KNKYHGGHET SPQELMEADR EVLLKLGRLA FEHLEKGNIM FYQEDLEQCG
     LDVTEASVYS GVCTEIFKRE SVIFQKPVYS FVHLSVQEFM AAVYMLHCFT TRNSEVVKDF
     LDGSPNTHVR RDLKMEDGNF TLDCFLERVM MKSLQSKTGH LDMFVRFIHG LSLKSNQKLL
     GGLVDQTENS PENIYKIINN LKKMNTNKMS PDRSINIFYC LIEMNDLSIQ QEIQEFLRME
     NRLERELSEI HCSALAYMLQ MLEEVLDELD LDMFNTSKEG KMRLIPVVRN CRKARLVGCR
     LSETHCEVVA SALMSSRSQL VELDLTGNVL PGPGVKLLCD GLASPYCKLK TLRLRGCRLS
     EISCDSLVSA LMSNPSHLKH LDMGLNNKLQ DSGMKLLCAF LENSESRLKT LSLTGVACAY
     LASALKSNPS HLTHLDMSGN NLEDSGVKHL CAFMETPNCK LQKLSLWGCR LSGTSCASIV
     SALNTNPSLL KRLDLRDNNL QDSDVEQLLD LVETWGSFCL HIK
//