ID A0A3B3U7G3_9TELE Unreviewed; 940 AA.
AC A0A3B3U7G3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Utrophin {ECO:0000313|Ensembl:ENSPLAP00000008868.1};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000008868.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000008868.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3U7G3; -.
DR Ensembl; ENSPLAT00000002173.1; ENSPLAP00000008868.1; ENSPLAG00000011888.1.
DR GeneTree; ENSGT00940000153467; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0045202; C:synapse; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd00176; SPEC; 2.
DR CDD; cd00201; WW; 1.
DR CDD; cd02334; ZZ_dystrophin; 1.
DR Gene3D; 1.20.58.60; -; 2.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR015153; EF-hand_dom_typ1.
DR InterPro; IPR015154; EF-hand_dom_typ2.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR InterPro; IPR000433; Znf_ZZ.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR12268; E3 UBIQUITIN-PROTEIN LIGASE KCMF1; 1.
DR PANTHER; PTHR12268:SF26; UTROPHIN; 1.
DR Pfam; PF09068; EF-hand_2; 1.
DR Pfam; PF09069; EF-hand_3; 1.
DR Pfam; PF00435; Spectrin; 1.
DR Pfam; PF00397; WW; 1.
DR Pfam; PF00569; ZZ; 1.
DR SMART; SM00150; SPEC; 2.
DR SMART; SM00456; WW; 1.
DR SMART; SM00291; ZnF_ZZ; 1.
DR SUPFAM; SSF47473; EF-hand; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 2.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS01159; WW_DOMAIN_1; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
DR PROSITE; PS01357; ZF_ZZ_1; 1.
DR PROSITE; PS50135; ZF_ZZ_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Synapse {ECO:0000256|ARBA:ARBA00023018};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00228}.
FT TRANSMEM 906..925
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 307..340
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 549..605
FT /note="ZZ-type"
FT /evidence="ECO:0000259|PROSITE:PS50135"
FT REGION 755..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 174..208
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 796..826
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 940 AA; 107781 MW; 76096EC4818EC549 CRC64;
LLHLKYVDGN KSKMVKALGN SEEAVFLQHR LDDMNQRWSD LKAKSANIRA HLEASAERWS
RLLGLLEELW RWICTKDEEL AKQMPVGGDV PTLLQQQNHC MVRTLNTSPL HCHLVISTLD
QARMFLADQP IEGPGEPRKN LQPKTEEKAR GLARAIRKQT GEVRERWERL KGHVGGWQAQ
VEQALERLQD LQSSMDQLDL HLTRAEETKA TWQPVGDLLI DSLQDHIDKT SAFREEITPL
RQDVRVVNEL AAELTPLDIQ LSSTASRQLD QLNMRWKSLQ VAVEDRLKLL QEAHRDFGPS
SQHFLSTSVQ LPWQRAVSQN KVPYYINHQT QTTCWDHPKM TELYQSLADL NNVRFSAYRT
AMKIRRLQKA LCLDLLDLSV AQNTFEQHKL TNNSHLLSVP DVINCLTSIY DGLEQEHKDL
VNVPLCVDMC LNWLLNVYDT YFVTLATTNY NNFIKILFNK LVQLRTGDTC DQRQLGLLLH
EAIQIPRQLG EVAAFGGSNI EPSVRSCFQH VNNKVELEPR QFVDWMRLEP QSMVWLPVLH
RVAAAETAKH QAKCNICKEC PIVGFRYRSL KHFNYDVCQS CFFSGRTAKG HKLNYPMVEY
CTPTTSGEDM RDFTKVLKNK FRSKKYFAKH PRLGYLPVQT VLEGDNMETL SQTPQLSHDD
THSRIEQYAS RLAQMERSNG SLPTDSSSAT GSMDDEHALI IQYCQTLGGE GSPSSQPQSP
AQILQAVERE ERGELERIIA QLEEEQRALQ REYEQLREQH GQRGAPAATP WESEGQSALP
DEADLLAEAK LLRQHKGRLE ARMHILEEHN KQLESQLHRL RQLLSERLGS EVYPVAVNTP
LCACVCPEEL LAPHNSSSDL ADVMEQINNS FPACSRKFPS PPSPPPTPPA SACLCFATRS
QKSPSFFLFF FVGQLPLFFY YYYYYYYYYY YYGRLQLAIL
//
