ID A0A3B3UFB5_9TELE Unreviewed; 450 AA.
AC A0A3B3UFB5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE SubName: Full=Regulator of G-protein signaling 6-like {ECO:0000313|Ensembl:ENSPLAP00000011302.1};
GN Name=RGS6 {ECO:0000313|Ensembl:ENSPLAP00000011302.1};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000011302.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000011302.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3UFB5; -.
DR STRING; 48699.ENSPLAP00000011302; -.
DR Ensembl; ENSPLAT00000018653.1; ENSPLAP00000011302.1; ENSPLAG00000014397.1.
DR GeneTree; ENSGT00940000157159; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IEA:InterPro.
DR CDD; cd04450; DEP_RGS7-like; 1.
DR CDD; cd00068; GGL; 1.
DR Gene3D; 1.10.1240.60; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR Gene3D; 4.10.260.10; Transducin (heterotrimeric G protein), gamma chain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR015898; G-protein_gamma-like_dom.
DR InterPro; IPR036284; GGL_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR047016; RGS6/7/9/11.
DR InterPro; IPR047017; RGS6/7/9/11_DHEX_sf.
DR InterPro; IPR040759; RGS_DHEX.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45746; LP21163P; 1.
DR PANTHER; PTHR45746:SF2; REGULATOR OF G-PROTEIN SIGNALING 6; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00631; G-gamma; 1.
DR Pfam; PF00615; RGS; 1.
DR Pfam; PF18148; RGS_DHEX; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00049; DEP; 1.
DR SMART; SM01224; G_gamma; 1.
DR SMART; SM00224; GGL; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF48670; Transducin (heterotrimeric G protein), gamma chain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS50058; G_PROTEIN_GAMMA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT DOMAIN 12..87
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 234..293
FT /note="G protein gamma"
FT /evidence="ECO:0000259|PROSITE:PS50058"
FT DOMAIN 309..424
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT REGION 200..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 450 AA; 52018 MW; 9CB552B627B8203D CRC64;
MEDIVTRIQD EKAGGVAIRT VKSFLSKIPS VVSGADIVQW LMKNLSIEDP AEAIHLGSLI
AAHGYIFPIS DHVLTLKDDG THYRFQSPYF WPSNCWEPEN TDYAIYLCKR TMQNKARLEL
ADYEAENLAR LQRAFARKWE FIFMQAEAQV KIDRKKDKAE RKILDSQERA FWDVHRPVPG
CVNTTEMDIR KCRREKNPHR VKKSVYGVPD DGQSQPSPIH ISSQPSRKPT KEDVQKEITF
LNIQLDRHCM KVSKVADSLM TYTEQFMEYD PFVSGVEPSN PWISDDATFW DMEASRDPSQ
QRVKKWGFSL EEALKDPAGR DQFLKFLESE FSSENLRFWM AVQDLKRRPL QEVSTRAQEI
WQEFLAEGAP SSINLDSHSY ERTSQNLKDP GRYSYEDAQE HIFKLMKSDS YARFLRSNIY
QDLLSARKKV SSSVGKSLTG KRLTGLMQSS
//
