ID A0A3B3UM74_9TELE Unreviewed; 380 AA.
AC A0A3B3UM74;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Growth/differentiation factor 11-like {ECO:0000313|Ensembl:ENSPLAP00000013973.1};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000013973.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000013973.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR AlphaFoldDB; A0A3B3UM74; -.
DR Ensembl; ENSPLAT00000022137.1; ENSPLAP00000013973.1; ENSPLAG00000018903.1.
DR GeneTree; ENSGT00940000166043; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd19388; TGF_beta_GDF8; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF166; GROWTH_DIFFERENTIATION FACTOR 11; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 268..380
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
SQ SEQUENCE 380 AA; 43299 MW; 73756410CA2C831C CRC64;
MNYCISADRY GGDQLVVLLT LILAPPTDAG LSLLDEDAGS HECSACVWRE QSKVLRLETI
KSQILSKLRL KQAPNISREV VNQLLPKAPP LQQLLDHHDF QGDASAQDEF MEEDEYHATT
ESVITMASEP EPLVQVNGKP SCCFFKFSPK LMFTKVLKAQ LWVYLRPLQQ TSTVYLQILR
LKPVTEQGSR HIRIRSLKIE LNSRAGHWQS IDFKHVLQNW FKQPHTNWGI DINAFDESGN
DLAVTSLRPG EEGLQPFLEV KVLETTKRSR RNLGLDCDEH STESRCCRYP LTVDFEAFGW
DWIIAPKRYK ANYCSGQCEY MFMQKYPHTH LVQHANPRGS AGPCCTPTKM SPINMLYFND
KQQIIHGKIP GMVVDRCGCS
//
