ID   A0A3B3UQZ3_9TELE        Unreviewed;       589 AA.
AC   A0A3B3UQZ3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Mitogen-activated protein kinase kinase kinase 3-like {ECO:0000313|Ensembl:ENSPLAP00000015136.1};
OS   Poecilia latipinna (sailfin molly).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000015136.1, ECO:0000313|Proteomes:UP000261500};
RN   [1] {ECO:0000313|Ensembl:ENSPLAP00000015136.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3UQZ3; -.
DR   Ensembl; ENSPLAT00000030575.1; ENSPLAP00000015136.1; ENSPLAG00000019016.1.
DR   GeneTree; ENSGT00940000164858; -.
DR   Proteomes; UP000261500; Unplaced.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd06653; STKc_MEKK3_like_u1; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000270; PB1_dom.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR017441; Protein_kinase_ATP_BS.
DR   PANTHER; PTHR48016; MAP KINASE KINASE KINASE SSK2-RELATED-RELATED; 1.
DR   PANTHER; PTHR48016:SF50; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19; 1.
DR   Pfam; PF00564; PB1; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   SMART; SM00666; PB1; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW   Transferase {ECO:0000256|ARBA:ARBA00022777}.
FT   DOMAIN          325..585
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          106..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        142..168
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         354
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ   SEQUENCE   589 AA;  66271 MW;  14721BC30C8CED30 CRC64;
     LRVKLEHERE KRIIPFQRPL KIKELLQKVT EAFGQQMDLF FMEKELLLPL KSQEDLDQAV
     LSLGNTSGTN GLLRILLKTP KNNPVSGSHC SLRMRIIETP AAYLQVNSRD KQSEMKSSRS
     LGDLKGSLLK GSERVRKHST GSLHTGRTSP PPGSVPEEQQ QIARQGSYTS IHSEGEFIPE
     TSDQNVSSAP RDKCCSTVFR VSERGAERWM GHKGKLNVSA SEGFTSVLPL SGRHGKGGTF
     PRQFQLPNRS KDYGRRTLPR SFMPQENLFQ LVPSSRTRSY NGDSSLTFSD LRSLGRTNFS
     SFFISATLDE QIHLQMRSPR APVNWRQGKL LGRGAFGEVY LCYDADTGRE LAAKQVPFDP
     DSQETSKEVN ALECEIQLLK NLRHDRIVQY YGCLRDLEHR KLTIFVEFMP GGSIKDQLKA
     YGALTEKVTR RYTRQILQGV SYLHSNMIVH RDIKGANILR DSSGNIKLGD FGASKRIQTI
     CMTGTGIKSV TGTPYWMSPE VINGEGYGRK ADVWSVACTV VEMLTQKPPW AEYEAMAAIF
     KIATQPTKPM LPEGVSDSCR DFLRQVFVEE KWRPTADILL SHPFVQSTF
//