ID A0A3B3V4Y9_9TELE Unreviewed; 335 AA.
AC A0A3B3V4Y9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=Alkyl transferase {ECO:0000256|RuleBase:RU363018};
DE EC=2.5.1.- {ECO:0000256|RuleBase:RU363018};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000020118.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000020118.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(2E,6E)-farnesyl diphosphate + n isopentenyl diphosphate = di-
CC trans,poly-cis-polyprenyl diphosphate + n diphosphate;
CC Xref=Rhea:RHEA:53008, Rhea:RHEA-COMP:13431, ChEBI:CHEBI:33019,
CC ChEBI:CHEBI:128769, ChEBI:CHEBI:136960, ChEBI:CHEBI:175763;
CC EC=2.5.1.87; Evidence={ECO:0000256|ARBA:ARBA00000976};
CC -!- SIMILARITY: Belongs to the UPP synthase family.
CC {ECO:0000256|RuleBase:RU363018}.
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DR RefSeq; XP_014883192.1; XM_015027706.1.
DR AlphaFoldDB; A0A3B3V4Y9; -.
DR STRING; 48699.ENSPLAP00000020118; -.
DR Ensembl; ENSPLAT00000014335.1; ENSPLAP00000020118.1; ENSPLAG00000002785.1.
DR GeneID; 106944613; -.
DR KEGG; plai:106944613; -.
DR CTD; 79947; -.
DR GeneTree; ENSGT00390000007879; -.
DR OrthoDB; 521455at2759; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0045547; F:dehydrodolichyl diphosphate synthase activity; IEA:UniProtKB-EC.
DR CDD; cd00475; Cis_IPPS; 1.
DR Gene3D; 3.40.1180.10; Decaprenyl diphosphate synthase-like; 1.
DR HAMAP; MF_01139; ISPT; 1.
DR InterPro; IPR001441; UPP_synth-like.
DR InterPro; IPR018520; UPP_synth-like_CS.
DR InterPro; IPR036424; UPP_synth-like_sf.
DR NCBIfam; TIGR00055; uppS; 1.
DR PANTHER; PTHR10291:SF43; DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS; 1.
DR PANTHER; PTHR10291; DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER; 1.
DR Pfam; PF01255; Prenyltransf; 1.
DR SUPFAM; SSF64005; Undecaprenyl diphosphate synthase; 1.
DR PROSITE; PS01066; UPP_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363018}.
FT COILED 87..114
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 335 AA; 38772 MW; 8E19004A0C10846B CRC64;
MSWIREGELN LLEKISANIL MAGPMPKHVA FIMDGNRRFA RKKKLERHDG HMQGFNKLAE
TLRWCKHLNI PEVTVYAFSI ENFKRSKEEV DGLLDLARQK FERLLEEQEN LEKHGVCIRV
LGDLNMLPLD LQEVIAKAVV MTKNHNKCFL NVCFAYTSRY EITNAVREMA WGVEQGLIKA
SDVSEALLSE CLYSSNSPNP DLLIRTSGEV RLSDFLLWQT SHSCLVFQSV LWPEYSFWNL
CEAIVQYQLN HKSIQKAREL HRDEQALQQL EADCACIAEH LQHQGNGKPA DAQRRQEALQ
HYTVAREERV QDFLQALKHK RDTFFTNLCS ETILT
//
