ID A0A3B3V6W9_9TELE Unreviewed; 506 AA.
AC A0A3B3V6W9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Neurofilament light polypeptide-like {ECO:0000313|Ensembl:ENSPLAP00000020768.1};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000020768.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000020768.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR AlphaFoldDB; A0A3B3V6W9; -.
DR Ensembl; ENSPLAT00000012693.1; ENSPLAP00000020768.1; ENSPLAG00000004004.1.
DR GeneTree; ENSGT00940000165501; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF8; NEUROFILAMENT LIGHT POLYPEPTIDE; 1.
DR Pfam; PF00038; Filament; 1.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}.
FT DOMAIN 20..331
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 354..506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 24..156
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 250..302
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 363..417
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 418..506
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 506 AA; 57262 MW; EA0BEC1A319EBAB6 CRC64;
MLLHQAAQIS SDFRAVRTQE RGQLQELNDR FASFIERVRE LEQQNRALEA ELLLLRQRHA
EPSRLRALYE QEARTLRAAV DEARAEQQTV LGQRERLEQT LNSLQGRYEE EMLAREEAEG
KLMEARREAD EAALGMAELE KGVETLLDEL TFLKRIHEGE VAELQTQVQL GVQLAVESEA
AAPDLSGALR DIRSQYERLA ARNMQAAEEW FRGKVGSLTE TVAQHSSAVK SSKDEAGEYR
RQLQARILEI DACRGLNVSL EKQLHEMEEK QSAEIAAMHD TIGELENELR GTKQEMAHYL
KEYQDLLNVK MALDIEIAAY RKLLEGEESR FSVGVPGGVA SLYSHSMVGI ISASHAQQAE
ASPPAEEEEE EEEEEAEEVK GEEGGEEQKE EEEEEQGEKE EEEEGGEQEE EKGEEEAKDE
EKEEKGESKK SEEKEEKGES KKSDEKEEKK ESKKSEEKAE KADAKKEDKP DVKEAAPKKD
EAKKEKVEEK AAKPEPAEEK STTGKK
//
