ID A0A3B3VCN8_9TELE Unreviewed; 444 AA.
AC A0A3B3VCN8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Vitronectin-like {ECO:0000313|Ensembl:ENSPLAP00000023540.1};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000023540.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000023540.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_014870934.1; XM_015015448.1.
DR AlphaFoldDB; A0A3B3VCN8; -.
DR STRING; 48699.ENSPLAP00000023540; -.
DR Ensembl; ENSPLAT00000005677.1; ENSPLAP00000023540.1; ENSPLAG00000008999.1.
DR GeneID; 106935131; -.
DR KEGG; plai:106935131; -.
DR CTD; 403026; -.
DR GeneTree; ENSGT00530000063751; -.
DR OrthoDB; 5310951at2759; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0030247; F:polysaccharide binding; IEA:InterPro.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR GO; GO:0006955; P:immune response; IEA:InterPro.
DR CDD; cd00094; HX; 1.
DR Gene3D; 4.10.410.20; -; 1.
DR Gene3D; 2.110.10.10; Hemopexin-like domain; 2.
DR InterPro; IPR000585; Hemopexin-like_dom.
DR InterPro; IPR036375; Hemopexin-like_dom_sf.
DR InterPro; IPR018487; Hemopexin-like_repeat.
DR InterPro; IPR020436; SMB_chordata.
DR InterPro; IPR036024; Somatomedin_B-like_dom_sf.
DR InterPro; IPR001212; Somatomedin_B_dom.
DR PANTHER; PTHR22917; HEMOPEXIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR22917:SF3; VITRONECTIN; 1.
DR Pfam; PF00045; Hemopexin; 3.
DR Pfam; PF01033; Somatomedin_B; 1.
DR PRINTS; PR00022; SOMATOMEDINB.
DR SMART; SM00120; HX; 4.
DR SMART; SM00201; SO; 1.
DR SUPFAM; SSF50923; Hemopexin-like domain; 1.
DR SUPFAM; SSF90188; Somatomedin B domain; 1.
DR PROSITE; PS51642; HEMOPEXIN_2; 4.
DR PROSITE; PS00524; SMB_1; 1.
DR PROSITE; PS50958; SMB_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..444
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017266767"
FT DOMAIN 20..62
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT REPEAT 119..163
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REPEAT 164..211
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REPEAT 212..262
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REPEAT 377..430
FT /note="Hemopexin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01011"
FT REGION 91..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 93..110
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 333..351
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 444 AA; 50459 MW; 352F8F02E54286DD CRC64;
MKAAVVLLGL AVLLDTAFGA EESCVGRCGS FNSRNKCQCD SMCVYYGSCC EDFYTFCPKK
VSRGDTFGEA EMDPNMSTTE QTPNLITVAP TVPSSLTPPP RAPQGPSPTV DPNAAPCSGL
PFDAFLQLKN GSIYAFRGLY FFELDEQSIL PGYPKLIEQV WGIAGPVSAA FTRINCQGKS
YIFKGNQYWR FDGDVLDEDY PRDISVGFED IPNDIDAAFA VPAPSHRGKE KAYFFKGDKY
YQYEFKHQPS HEECVSLSRT SQSVLFTRYT DLFCEQPLEN LFTDLFESFH THNSSPQLTF
RDWKGISPPV DAALVGKVSL SPKPTISSPP ARRRSRGQRR RPSKRRFPQR RRQSRFVFDD
LWFDDDLFDF GIDYSDTAEV ATVQEYKSTP FQNVYFFKKD KYYRVSLQTK RVDSVSPPYP
RSIAKYWLGC EEEYLIDSSR AEKK
//
