ID A0A3B3VF11_9TELE Unreviewed; 1834 AA.
AC A0A3B3VF11;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Protein Shroom3-like {ECO:0000313|Ensembl:ENSPLAP00000024345.1};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000024345.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000024345.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the shroom family.
CC {ECO:0000256|ARBA:ARBA00006469}.
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DR STRING; 48699.ENSPLAP00000024345; -.
DR Ensembl; ENSPLAT00000003625.1; ENSPLAP00000024345.1; ENSPLAG00000010457.1.
DR GeneTree; ENSGT00940000157778; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 6.10.250.3120; -; 1.
DR InterPro; IPR014800; ASD1_dom.
DR InterPro; IPR014799; ASD2_dom.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR027685; Shroom_fam.
DR PANTHER; PTHR15012; APICAL PROTEIN/SHROOM-RELATED; 1.
DR PANTHER; PTHR15012:SF33; PROTEIN SHROOM3; 1.
DR Pfam; PF08688; ASD1; 1.
DR Pfam; PF08687; ASD2; 1.
DR Pfam; PF00595; PDZ; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS51306; ASD1; 1.
DR PROSITE; PS51307; ASD2; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|PROSITE-ProRule:PRU00637};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701}.
FT DOMAIN 20..105
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 878..1000
FT /note="ASD1"
FT /evidence="ECO:0000259|PROSITE:PS51306"
FT DOMAIN 1515..1819
FT /note="ASD2"
FT /evidence="ECO:0000259|PROSITE:PS51307"
FT REGION 112..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 352..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 451..1005
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1056..1088
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1094..1113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1124..1145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1160..1190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1271..1312
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1324..1346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1360..1431
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1508..1539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1618..1637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..143
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..187
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 481..503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 535..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..603
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 690..704
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 752..766
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 767..784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 834..848
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 883..897
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 955..969
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 979..993
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1160..1178
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1272..1298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1376..1391
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1394..1431
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1834 AA; 199623 MW; E73F5BBCCE94D602 CRC64;
MERRGRAGLQ PAGGGEGGGW VLVEARLQGG APWGFTVQGG LEHGQPLIIS KVEEGGKADS
VERPLLVGDE IIIINDVELS GYRQEAIALI KGSFKTLQLT VRREFDPGYI EEFTSPNSGA
ALRLPSPPPD LRFQSPSLSP PPSQETPSSN HSRRCSAVQL RIRNRRSEPA SRPHSWHSTK
LGDDQPDLEQ MESMGPVWGH SYPSSASTTD LSAGFDPSGG YLRKSPDQYS SRGSMESLDP
AQSSHHHPVT QQQLPLGHRS QTGPNPAYSS CQQLSSARSN SIDLLHSKRD SAYSSFSTSS
SIPEYLASTP SFGPERSCSL DAVPQRGAGS AEMLQADIRY VRAVYDAQQG LTQEQELNSS
RTGPRSGPRD LQGSVGGVCY RGANGSRGGG VPASNRHSVG PIWGQAASRS SYESLKGAPA
PPRRSDSYAV IRNHERPNSW SSLDHARSLR SLQSSSLHHS SGPVASAKAS FGAEGQLHTV
MEKSPESSPT TKPRQGAGFS QPPSPTGPSS PPSRLILPAG VYPVPQPEPQ YAQTPSAGPG
PSGVFTALTK ESSRQPALRD DRTTENGHQG IGSSPYSRSS YSGPGSSQLR SRLPEADSWH
QQPESNSETH KPHLKTPGAG SEGPTGPHKP YRNLSQNLDD PLLKGQQEQN HRITPVHSVP
DLRTASSQGR SESRDNTRPR EPPTVPSEPA GSSRVAQGQV PPHPSAQWSH RDPDSDHPLT
RLEIALAEVQ RCAVPDGPDG GQSPARSLSV LEKVSHFERR RDGGKQRSFS TNSYCKSSHL
GVTDKGRSSP CGAEDLRNML ERSTKGTKTH RTMSYRGGGN EYMKHRLPAD PVSALQRSRS
SFQLDGSKDG DVNRNFPYRP EPQEAADPLQ DRSYRDSVKD AQPNVLRSAS FRQRDLSSPP
PVVSGPQPFP NPAKYNSLEK KGPKTKPKPQ GIVMPPVTSP HTPKERHAVS PDNGGQSPPP
LPSVPPVGPP ALTRICGRKR LTADQKKRSY SEPENMNEVG VSDPETAALF RRGGETSVAD
RRKMFELAAS HVGAGVSRSD LRQLRQDALV EYMERKRGMR RDEAGQRTGS RPRSAYFHPE
QGYHTDTYSL SSTSSMLSLQ DPGPDQGVPA LGSDRWSLQS NLFYPGRVTT PRPPAQPIPG
SSLDLHTQIS QDLNPEAQIN RHSQSGTRDS NRSQDRQIAE PQYKPGLSTK VNEALQRVGS
VHRSGRSASA EDLLERLENK YSPQHIRSRS SPTADKLSQN LISGDIKSFD VSFSESGRCA
LAADRPADIH GSAEFSSQSN RFNENSDRPT ASPQDVSHTP VSRRERQRNG ERLRAYSTST
LAASVGLPSP FSSPGNQQDG GAAEWTSGKR LSQANLDAIT FPGIPQTGGR QTRRSLSDGT
AEDEHRGRTL SLELTGEISE NTKPVSPVTS APPPCRKTSG SSTSSHQSVH PHLSSLRISE
SSLFEQQPLQ TSTGNLQEFD DVFLTNPPLP PPPPLTPPIK ETNIMEDFPP LPPPPPPAEM
EADLQPLQSS NPETLNNSVP IRTSSAQSAP PLKPSNSTED VFVFQYQPLP RREKSPEELR
VEALTQQVVL QDPSLAPLLD TWGGECTMKL MEEIFSNGSL TGEAPGSSLP GQRIQAVCDQ
SSDQTKETDV DEDENDVTTR KGELCEALRL CVAAMQREKA ALAEEQRRHQ AAGAGMEALI
QQLKANEKEK YSMFIGDLER IVNLLLSLCS RLSRVDKSLL SLDRDGGLTE DAAEERDSLH
HKRSLLLRQT EDARELKENL DRRQRVVTAI LTGYLTEAQL HDYRRFVSAK PSLLIRQRQL
DDLIRQREEQ LARLAESLPP SPAHSVRSTA VTSL
//
