ID A0A3B3VG53_9TELE Unreviewed; 138 AA.
AC A0A3B3VG53;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=TNFR-Cys domain-containing protein {ECO:0000259|PROSITE:PS50050};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000023952.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000023952.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR AlphaFoldDB; A0A3B3VG53; -.
DR STRING; 48699.ENSPLAP00000023952; -.
DR Ensembl; ENSPLAT00000004626.1; ENSPLAP00000023952.1; ENSPLAG00000009743.1.
DR GeneTree; ENSGT00940000153259; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR GO; GO:0043123; P:positive regulation of canonical NF-kappaB signal transduction; IEA:InterPro.
DR GO; GO:0046330; P:positive regulation of JNK cascade; IEA:InterPro.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 1.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR047526; TNR19/27/EDAR.
DR PANTHER; PTHR12120; TNFR-CYS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12120:SF10; TNFR-CYS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00020; TNFR_c6; 1.
DR SMART; SM00208; TNFR; 2.
DR SUPFAM; SSF57586; TNF receptor-like; 1.
DR PROSITE; PS00652; TNFR_NGFR_1; 2.
DR PROSITE; PS50050; TNFR_NGFR_2; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 76..116
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 76..116
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
SQ SEQUENCE 138 AA; 14763 MW; 3CBD6B0EDF621759 CRC64;
LEIICLNCDL SIFFTFILLL GPFLFLFITL NLIPRCDQTE YLHHNGTCVA CPVCKPGEQL
SGDCGFGYGG DGVCIPCEAG TFSTDTSVDP CRRCTQCNLL NRLALAACSP TSDSVCGHCL
PGLVPSTAPE KTPVAFCY
//
