ID A0A3B3VIG4_9TELE Unreviewed; 503 AA.
AC A0A3B3VIG4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Cdc42-interacting protein 4 homolog {ECO:0000313|Ensembl:ENSPLAP00000024564.1};
GN Name=TRIP10 {ECO:0000313|Ensembl:ENSPLAP00000024564.1};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000024564.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000024564.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cell cortex
CC {ECO:0000256|ARBA:ARBA00004544}. Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Lysosome
CC {ECO:0000256|ARBA:ARBA00004371}.
CC -!- SIMILARITY: Belongs to the FNBP1 family.
CC {ECO:0000256|ARBA:ARBA00009426}.
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DR RefSeq; XP_014889441.1; XM_015033955.1.
DR AlphaFoldDB; A0A3B3VIG4; -.
DR STRING; 48699.ENSPLAP00000024564; -.
DR Ensembl; ENSPLAT00000003060.1; ENSPLAP00000024564.1; ENSPLAG00000010859.1.
DR GeneID; 106948341; -.
DR KEGG; plai:106948341; -.
DR CTD; 108179043; -.
DR GeneTree; ENSGT00950000183047; -.
DR OrthoDB; 2995634at2759; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd07653; F-BAR_CIP4-like; 1.
DR CDD; cd11628; HR1_CIP4_FNBP1L; 1.
DR CDD; cd11911; SH3_CIP4-like; 1.
DR Gene3D; 6.10.140.470; -; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR011072; HR1_rho-bd.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15735:SF17; CDC42-INTERACTING PROTEIN 4; 1.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS51860; REM_1; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 1..263
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 323..400
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 443..503
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT COILED 105..167
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 503 AA; 57408 MW; 3B7FED15AF7C8FA8 CRC64;
MDWGTDLWDQ NDVIDKHTQS GLDLLERYIK FVKERTEIEQ NYAKQLRNLT KKYSKRGGKD
EQECKFSNHA SFQEILNELG DYAGQREVVA ENMTANICDK LTKYLQDLKQ ERKTHLSDVK
KAQQNLESSF KHLENIKKRF AKEWAEADKA TQQAEKTEND SNATKVEVDK AKSHALARTR
VAEECRNNYA AELQKYNKEQ NYFYYTEIPQ IYNKLQVMDE RRIQQLAEGY CLFSHIEKDV
LPIISKCLEG IAAAGTKIDH KKDSKLLIEQ HKSGFDRPTD VEFEDYSQGI KPSNSESTLN
PLKGRKHKIF KKHKSPPAEN FSHLPPEQRK KKLQAKIDDI TKELTKEQDS GEALEKMRGV
YEQNPQMGDP SSLEPQITQT SQNIGRLRGE LAKYETWLSE AVGGEDASHN TTNNNSQSGI
IATRNSSSNV YAEFDDEFDD IESPVGQCTA LYTFAGNSEG TISITEGELL SVMEEDKGDG
WMRVLRASGQ EGYIPTSYVK LTP
//
