ID   A0A3B3VKX0_9TELE        Unreviewed;       471 AA.
AC   A0A3B3VKX0;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Interleukin-1 receptor type 1-like {ECO:0000313|Ensembl:ENSPLAP00000025646.1};
OS   Poecilia latipinna (sailfin molly).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000025646.1, ECO:0000313|Proteomes:UP000261500};
RN   [1] {ECO:0000313|Ensembl:ENSPLAP00000025646.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the interleukin-1 receptor family.
CC       {ECO:0000256|ARBA:ARBA00009752}.
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DR   AlphaFoldDB; A0A3B3VKX0; -.
DR   STRING; 48699.ENSPLAP00000025646; -.
DR   Ensembl; ENSPLAT00000000303.1; ENSPLAP00000025646.1; ENSPLAG00000012817.1.
DR   GeneTree; ENSGT01090000259985; -.
DR   Proteomes; UP000261500; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR015621; IL-1_rcpt_fam.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR11890; INTERLEUKIN-1 RECEPTOR FAMILY MEMBER; 1.
DR   PANTHER; PTHR11890:SF47; INTERLEUKIN-1 RECEPTOR TYPE 1-LIKE; 1.
DR   Pfam; PF01582; TIR; 1.
DR   PRINTS; PR01537; INTRLKN1R1F.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50835; IG_LIKE; 2.
DR   PROSITE; PS50104; TIR; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        247..270
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          34..121
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          133..232
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   DOMAIN          294..459
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   471 AA;  53393 MW;  19802DF3D9E8E1D3 CRC64;
     MTHSGSYICE KRNKTKPSKR RFRVLVSGSN CPDPSEEILA TKETGEFLQC KQKEIFRLNL
     PRKIRWTKDC QQVQPDGESI SLNTNGFMRL AEVSEADAGK YTCHIDVTVD GRNYTAARSV
     QMTVKNGTPD LFPEIHVVRP KNEVVIVEVG KRAELHCKAY TGFSEDEEIA MYWIINGTYA
     SDISGLAESW KFVHERGKVF GQSTLSIATV RNEFLNIPIN CHISSPAEEK VGEVRLQEAD
     PTEHNTFYMI VSLWLSALFT ILILTAFFLI CKVNLFLAYR ALKTLFSKQV PDGKLYDAYV
     SVGQSAMLGL DGVACFTLRL LPEELEQKHG YSLFIRGRDD RPGEAVHDVI SAAVRQCRRL
     LIVLSSAGKS KETAQFWENH NLLTYEQKVG LHDALMRNDP KVILVEVDGP VDYSQLPESL
     RYIKRTQGAL EWKNSFAETN KLTQMYLKRN FWKSLRCHMP AVPARTPQSI A
//