ID A0A3B3VUA8_9TELE Unreviewed; 1243 AA.
AC A0A3B3VUA8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Bromodomain containing 1 {ECO:0000313|Ensembl:ENSPLAP00000028626.1};
GN Name=BRD1 {ECO:0000313|Ensembl:ENSPLAP00000028626.1};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000028626.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000028626.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_014890316.1; XM_015034830.1.
DR AlphaFoldDB; A0A3B3VUA8; -.
DR STRING; 48699.ENSPLAP00000028626; -.
DR Ensembl; ENSPLAT00000022777.1; ENSPLAP00000028626.1; ENSPLAG00000018166.1.
DR GeneID; 106948932; -.
DR KEGG; plai:106948932; -.
DR CTD; 569574; -.
DR GeneTree; ENSGT00940000157236; -.
DR OrthoDB; 163389at2759; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd05512; Bromo_brd1_like; 1.
DR CDD; cd15572; PHD_BRPF; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR019542; Enhancer_polycomb-like_N.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF17; BROMODOMAIN-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF10513; EPL1; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SMART; SM00249; PHD; 2.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 222..272
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 276..398
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 592..662
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 1114..1197
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 73..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 779..858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 897..951
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 970..1004
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 528..567
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 73..90
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 421..436
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 792..817
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 837..858
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 976..996
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1243 AA; 139609 MW; 194FA166F7BD38F0 CRC64;
MKKKARQHRP AVPQRAQSPI KPSPNKQILT YAQAQRMVEF ELDGRIHRLS IYDKLDVISD
DDPMVQEMME CTSNKENADK PQQQVRQRSA RLKNNQEKRN AALGIAGNSE AGGHHAAGPA
APKLPEPKFR VVEYNLPAVP KRPAAFYKYI EKTEEELDEE TEYDMDEEDY AWLELVNEKR
KSEGMSQVSH NVFEFLIDRF EKELHLESLD QASEKQPAVD EDAVCSICMS GECHKSNTIL
FCGVCGVSVH QECYGVPYVP ESHWLCRHCL QLPTQPADCI LCPNKGGAVK KTDDDRWGHV
VCALWVPEVG FANTTFIEPI DGVGQIPSAR WKLTCYICKE KSVGACIQCH KANCYTAFHV
TCAQKAGLFM KMEPINEVTD TGEPILSVKK TAYCGAHTPN GCVRRPLSIY EDAKRKNGLC
KRANKGRGDD KEHFKGKQQK KKCKSKKPEP DEESEAAAPA TVPSFPAHRL QTILNQVSIQ
KKRAFVELVL NYWTLKRRSR NGVPLIRRLQ TCLQAQKNSQ PRQNEEESRA LKEQLKEWHR
LRHDLERARL LLELIRKREK LKREEIKLHE TVLEMKLTPF SILLRALLDQ LQAKDQAKIF
TQPVDVNEVP DYLDHIKRPM DFSTIRQRID AQAYTNLDQF EADFNLIVDN CMKYNSKDTY
FYRAAVRLRD QGGVLLRKAR RDVEQMGFDA ESGMHLSEAP EVKAPPSFSW EDVDRLLVPA
NREHLPLDKQ LQLLLEKFDL TCAMKTSPSR SKRLKLLKKT INDVRNEISL KKLLPSHHHS
SVFAAAPSPP ELDKSTEDRP KSNGHFQDDE GDKSLPPKLE PPDALPPLLR SDADSEPPTL
KPIDDARDGA ELTRGKRPRL DGDAAELLSS APRLNGHSLQ SALLDGDVSV LATPTFAEPT
GTANHRTAVV FRKSKAAGAH GPPESEDRED DGADGGSGEQ DGENKDGSQL GAKSFLSVVI
PRLETLLHSK KRKRSGSRCR EVEEEETEHT EEGASPGKRL DTGLSRGFLE LDEEKEVEKT
RRTSRAVEPR RRCASESSIS SCSSLQGSAS TILSLPKCGK GKPALVRRNT VDDKSELIAC
IESGNFAKAA RIAAEVGNSN IWMPASAATV ALEPLKLVWA KCSGYPSYPA LIIDPHMPRV
GCQHNGVSIP IPPMDVLRIG EQMQYKAEEK LHLVLFFDNK RSWQWLPRSK MVPLGIDKTI
DKIKLMEGRT SSIRKAVQIA FSRAMNHLSL VQDEQVSDLS DVD
//
