ID A0A3B3VVP9_9TELE Unreviewed; 1118 AA.
AC A0A3B3VVP9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=Poly [ADP-ribose] polymerase {ECO:0000256|RuleBase:RU362114};
DE Short=PARP {ECO:0000256|RuleBase:RU362114};
DE EC=2.4.2.- {ECO:0000256|RuleBase:RU362114};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000029123.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000029123.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the ARTD/PARP family.
CC {ECO:0000256|ARBA:ARBA00024347}.
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DR AlphaFoldDB; A0A3B3VVP9; -.
DR Ensembl; ENSPLAT00000030612.1; ENSPLAP00000029123.1; ENSPLAG00000021665.1.
DR GeneTree; ENSGT00940000160555; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.228.10; -; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR031273; PARP4.
DR InterPro; IPR012317; Poly(ADP-ribose)pol_cat_dom.
DR InterPro; IPR013694; VIT.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR46530; PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP4; 1.
DR PANTHER; PTHR46530:SF1; PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP4; 1.
DR Pfam; PF00644; PARP; 1.
DR Pfam; PF08487; VIT; 1.
DR Pfam; PF13768; VWA_3; 1.
DR SMART; SM00609; VIT; 1.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF56399; ADP-ribosylation; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS51059; PARP_CATALYTIC; 1.
DR PROSITE; PS51468; VIT; 1.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|RuleBase:RU362114};
KW NAD {ECO:0000256|RuleBase:RU362114};
KW Transferase {ECO:0000256|RuleBase:RU362114}.
FT DOMAIN 217..428
FT /note="PARP catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51059"
FT DOMAIN 448..575
FT /note="VIT"
FT /evidence="ECO:0000259|PROSITE:PS51468"
FT DOMAIN 702..869
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 1118 AA; 125389 MW; C394D69DD4AC6313 CRC64;
MDTVTFSVGL QTGISLTFLL FVSQINLKIM LEQNKSATVF QQEAAVMDQL VFLSTSEEAV
DVYKELSEEL ERSELQRMSS LPVTFNPLLT LMFLTFSLND LQLLLEEKLN SGELSPDVAA
FVEFLWTEAH GCLGNILRVP ISGLSLNDVG LHRSAVRSGS DPRLRPDEAV AVFFLLPHRE
PRPQSPTARF LSQKLDLCQL IRDVLNVSEM TMNDPKPSSV GKYRALRCGM EAVPRDNHHK
PFWKENNKHL CVSRPVEIQQ IMRVSRAVEL LRFQSEIGNV TPLLHASSPN NFVGILSRGL
LLPRVVVEQL GIKRTDYGRL GSGIYFGDAV STSLNYAKPS ETDGSRLLLV CDVALGVCKD
LNEEDKTLTE APQGYHSVHG VRQTNKTTSE FTNPKLLFKD DEYVVYSLDQ VKMKYVVQFR
VEGDEQKDFN LTSELVEEDL ENVKNPLKRI KAGLLDSSGQ RLPLQAVHVK CKLMDLLSQV
IIFQKYTNQS SVPIEAKYVF PLDSAAVCGF EAFINGKHVV GEVKEKETAR KEYKQAIAKG
HGAYLMDQSA PDVFTISVGN LPPGATVLIK VTFVSELVVE NGSILFSLPG SVAPWQKSSA
LNETTQVGGR FTLDMSVEMP FEILSLTCIT HQVKIKRMDC KAVVSVLPGQ VMGSDGFQMS
VTLSEVHLPR MWVEKHPDKD SQACMLVFYP NFEFDSSSEG SEVVLLLDTS ESMKGESLQL
AQKIALQVLK NLKNDVKINI VLFGTGWYKS RELSSSSSSP EAAELPVQRL PHAGLRTELW
RPLRALSLLP PSAGVRNLLL LSDGHIQNAA ATLQLLRDNA QHSRLFTCGF SSTANRHMLR
ALAQAGGGAY EFFDSKAKHT WAEKVERQVK RMSSPGCSSV SVKWQQFNPR APPVQAPKQL
NSLFNDCHTL VYGFVPHCTQ ATLLGDLRGQ ELQTMVSTTE LQKTRGTFLH KLTARALIRD
YEDGNLDITE AEHEGKKAEL KSFIIDLSKE FSILSQFTSF VAIEERDSGK PDDGVIDIPK
LIAEEDVDFL PNITWTLPED KEKVKIFLLI LHMLWNCSEV QDFLYAIYMS NQLYKKKFSF
LPEYSFWGIR LLLNICHSIT AEWVRRPHLF SLFYYFPQ
//
