ID A0A3B3W121_9TELE Unreviewed; 466 AA.
AC A0A3B3W121;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Voltage-dependent L-type calcium channel subunit beta-3 {ECO:0000256|ARBA:ARBA00019004};
DE AltName: Full=Calcium channel voltage-dependent subunit beta 3 {ECO:0000256|ARBA:ARBA00030522};
GN Name=CACNB4 {ECO:0000313|Ensembl:ENSPLAP00000030589.1};
OS Poecilia latipinna (sailfin molly).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48699 {ECO:0000313|Ensembl:ENSPLAP00000030589.1, ECO:0000313|Proteomes:UP000261500};
RN [1] {ECO:0000313|Ensembl:ENSPLAP00000030589.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the calcium channel beta subunit family.
CC {ECO:0000256|ARBA:ARBA00010836}.
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DR AlphaFoldDB; A0A3B3W121; -.
DR Ensembl; ENSPLAT00000031438.1; ENSPLAP00000030589.1; ENSPLAG00000021862.1.
DR GeneTree; ENSGT00950000182837; -.
DR Proteomes; UP000261500; Unplaced.
DR GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR CDD; cd12043; SH3_CACNB4; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR046937; CAB1-4_N_A-dom.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR008079; VDCC_L_b3su.
DR InterPro; IPR000584; VDCC_L_bsu.
DR PANTHER; PTHR11824:SF15; CALCIUM CHANNEL, VOLTAGE-DEPENDENT, BETA 4B SUBUNIT; 1.
DR PANTHER; PTHR11824; VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF12052; VGCC_beta4Aa_N; 1.
DR PRINTS; PR01626; LCACHANNELB.
DR PRINTS; PR01696; LCACHANNELB3.
DR SMART; SM00072; GuKc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 57..126
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 14..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 364..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..391
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..419
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 424..438
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 466 AA; 52912 MW; 1207B79C28E49AB2 CRC64;
MYDNLYLHGF EDSEAGSADS YTSRPSDSDV SLEEEREVRQ EREQQAAVQL ERAKSKPVAF
AVRTNVSYCG ALDEDVPVPA TAISFDAKDF LHIKEKFNND WWIGRLVKEG CEIGFIPSPL
KLENIRLQQE QKRGRNHLLC ASSVELFWAA FSTEHIPPYD VVPSMRPVVL VGPSLKGYEV
TDMMQKALFD FLKHRFDGRI TITRVTADIS LAKRSVLNNP SKRAIIERSN TRSSLAEVQS
EIERIFELAR SLQLVVLDAD TINHPAQLLK TSLAPIIVHV KVSSPKVLQR LVKSRGKSQS
KHLNVQLVAA EKLSQCPPEM FDIILDENQL EDACEHLAEY LEAYWKATHT SMATPLNPLM
GRNLGPTTLT PYPTSISGLQ SQKMRQSNHT GDHSTANERR NLMTSDENYH NERAHKGRNR
MSSGSQHSRE QQDPYQDYQD PYQDAYKPHR NRSSPGSYSH DSRQRL
//
