ID   A0A3B3WCJ1_9TELE        Unreviewed;       658 AA.
AC   A0A3B3WCJ1;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Nucleoporin NUP42 {ECO:0000256|ARBA:ARBA00039886};
DE   AltName: Full=Nucleoporin-like protein 2 {ECO:0000256|ARBA:ARBA00042384};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000000397.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000000397.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- FUNCTION: Required for the export of mRNAs containing poly(A) tails
CC       from the nucleus into the cytoplasm. {ECO:0000256|ARBA:ARBA00037262}.
CC   -!- SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000256|ARBA:ARBA00004335};
CC       Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004335};
CC       Cytoplasmic side {ECO:0000256|ARBA:ARBA00004335}. Nucleus, nuclear pore
CC       complex {ECO:0000256|ARBA:ARBA00004567}.
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DR   RefSeq; XP_014859922.1; XM_015004436.1.
DR   AlphaFoldDB; A0A3B3WCJ1; -.
DR   Ensembl; ENSPMET00000015948.1; ENSPMEP00000000397.1; ENSPMEG00000001177.1.
DR   GeneID; 106928291; -.
DR   KEGG; pmei:106928291; -.
DR   OrthoDB; 325136at2759; -.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 2.
DR   InterPro; IPR000571; Znf_CCCH.
DR   InterPro; IPR036855; Znf_CCCH_sf.
DR   InterPro; IPR008913; Znf_CHY.
DR   InterPro; IPR037274; Znf_CHY_sf.
DR   PANTHER; PTHR46527:SF1; NUCLEOPORIN NUP42; 1.
DR   PANTHER; PTHR46527; NUCLEOPORIN-LIKE PROTEIN 2; 1.
DR   Pfam; PF00642; zf-CCCH; 1.
DR   Pfam; PF14608; zf-CCCH_2; 1.
DR   Pfam; PF05495; zf-CHY; 1.
DR   SMART; SM00356; ZnF_C3H1; 2.
DR   SUPFAM; SSF90229; CCCH zinc finger; 2.
DR   SUPFAM; SSF161219; CHY zinc finger-like; 1.
DR   PROSITE; PS50103; ZF_C3H1; 2.
DR   PROSITE; PS51266; ZF_CHY; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW   ProRule:PRU00723}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00601}.
FT   DOMAIN          18..46
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50103"
FT   DOMAIN          91..118
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50103"
FT   DOMAIN          543..611
FT                   /note="CHY-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51266"
FT   ZN_FING         18..46
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT   ZN_FING         91..118
FT                   /note="C3H1-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT   REGION          50..88
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          316..356
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          635..658
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        59..76
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        329..356
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   658 AA;  74402 MW;  82774EA0F832A30B CRC64;
     MENEGEVKTE EEKAESFPQT QQLCRFFSQG RHCHFGKRCR FLHVREDEKD HEKKSFESPS
     QPDFTPSNSQ DGGQLEGDNS ALAHNPKFVP GSARRPCRYF LSGHCTMEDR CHFWHPPQLP
     PLDDPSVTAI RSKSTPRHPP EPHPGGLQEV KLCEMTEDTA KQLRDTEIRQ LKKRFPKDQL
     IIQERSDGKL TYYRASVEAT DPDWPFDLKE VDIMVSFPDN YPLEIFTLEI PLDQNLPSVM
     AKHVQEASLE WLQAKHATNQ LLGKVELLFR PFLRWLDRSL ERLFTEGARQ LKKDIDLEKA
     GLQFITYQEL QISVTETSDP ASGVAGDEDA RNSTEKTEDV DSEEEEHQKP IQSDEGQLLE
     EDASHLVENI RISDPRRGTE VKLLGLRLGE NTATVTAQRI TVCLQCNRCK VTADLTLTGR
     TACSAQCDKC DAGINAAFRP CMIHHYSDVL GYLDLQNATA SDLVLQDCDL TVGCLSCSQE
     IPVESVFYGQ TKEFNCENCH SKLSILAEST RFQYIQPRSS SKTGPSGVSY KTIRDPAVQK
     GKPLPDKGTC KHFKQSHRWL RFPCCGRAYA CDVCHDENQD HPMELATRMI CGFCAKEQPF
     GNGKPCVSCG SMMTRGTRTS HWEGGLGCRN KVKMSRNDRQ KHTNTNKTVS RKAASEKK
//