ID   A0A3B3WFN5_9TELE        Unreviewed;       670 AA.
AC   A0A3B3WFN5;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Tripartite motif containing 25 {ECO:0008006|Google:ProtNLM};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000001502.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000001502.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_014866413.1; XM_015010927.1.
DR   RefSeq; XP_014866414.1; XM_015010928.1.
DR   AlphaFoldDB; A0A3B3WFN5; -.
DR   STRING; 48701.ENSPMEP00000001502; -.
DR   Ensembl; ENSPMET00000014097.1; ENSPMEP00000001502.1; ENSPMEG00000002424.1.
DR   GeneID; 106932298; -.
DR   KEGG; pmei:106932298; -.
DR   CTD; 7706; -.
DR   OrthoDB; 5359093at2759; -.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   CDD; cd19769; Bbox2_TRIM16-like; 1.
DR   CDD; cd16597; RING-HC_TRIM25_C-IV; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 4.10.830.40; -; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR003879; Butyrophylin_SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR006574; PRY.
DR   InterPro; IPR003877; SPRY_dom.
DR   InterPro; IPR027370; Znf-RING_euk.
DR   InterPro; IPR000315; Znf_B-box.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR25465:SF40; E3 UBIQUITIN_ISG15 LIGASE TRIM25; 1.
DR   Pfam; PF13765; PRY; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   Pfam; PF00643; zf-B_box; 1.
DR   Pfam; PF13445; zf-RING_UBOX; 1.
DR   PRINTS; PR01407; BUTYPHLNCDUF.
DR   SMART; SM00336; BBOX; 2.
DR   SMART; SM00589; PRY; 1.
DR   SMART; SM00184; RING; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Immunity {ECO:0000256|ARBA:ARBA00022859};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          21..59
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          479..670
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
FT   REGION          379..477
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        383..398
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        428..445
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        453..471
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   670 AA;  74788 MW;  10AFBEEF8BFD48A9 CRC64;
     MMAEADDSGF SLMSLEDELT CSICLSTFDC PVTIPCGHNF CQNCLLATWK DSYSCPQCRT
     LFATRPELKK NTVLSTVVET FRVRSNKTEG GGGAAAASKP EKKRDVVRCD TCMEAEAAQT
     CLTCMASFCE EHLRPHRENP IFRLHQLSPP VGDLMERICT DHHKLMELFC SQHQRPICSL
     CLQQVHKGCS FTSPEEQRSK KEVDLREKLV FLDGKLSKNE SVISQMRVMQ NKLRESAIHR
     KSALSAGYQQ MRDMMTREEG DALKAIDKEV ETGETKIRGL ISKFSENVDN IGKAKEEIFC
     LLGQSQTLAF LQTSFNLPQA VSYDPYSPRI TLDSKKVVQS EAFALTLKNY LTELLKQPVE
     ARIPKLIADI NTGTFAAGER AASASGHSTT SLGQESDPSF PLPNPRLPRS HSPAPQAKPA
     QKKKPQKAPK NPSLTTETNP GNKKLGKSIE NLMEFGVKEK PRGRPAAAEN KEVTETTDIP
     SEISSAEKRS DLMKYGTVLN FDQRTAHKRI ELSENFTKAS VSDEHTNYPD CPERFAVCSQ
     VMASKGFSAG RHYWEVRLSS NNFIGIGLAY SSIDRKGPTS RLGRNSKSWC VEWFNVKLSA
     WHNSSEAVLV NPNPKRVGVL LDCEEGRATF YNVADRAYPF HSFSFQFAEA VYPAFWIFSS
     GSYITLCKLQ
//