ID A0A3B3WK65_9TELE Unreviewed; 852 AA.
AC A0A3B3WK65;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=RNA binding motif protein 5 {ECO:0008006|Google:ProtNLM};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000003198.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000003198.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_014852463.1; XM_014996977.1.
DR AlphaFoldDB; A0A3B3WK65; -.
DR STRING; 48701.ENSPMEP00000003198; -.
DR Ensembl; ENSPMET00000011252.1; ENSPMEP00000003198.1; ENSPMEG00000004295.1.
DR GeneID; 106923737; -.
DR KEGG; pmei:106923737; -.
DR CTD; 10181; -.
DR OrthoDB; 298711at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd12755; RRM2_RBM5; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 1.
DR InterPro; IPR000467; G_patch_dom.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR041591; OCRE.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR034993; RBM5_RRM2.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR001876; Znf_RanBP2.
DR PANTHER; PTHR13948; RNA-BINDING PROTEIN; 1.
DR PANTHER; PTHR13948:SF21; RNA-BINDING PROTEIN 5; 1.
DR Pfam; PF01585; G-patch; 1.
DR Pfam; PF17780; OCRE; 1.
DR Pfam; PF00076; RRM_1; 2.
DR Pfam; PF00641; zf-RanBP; 1.
DR SMART; SM00443; G_patch; 1.
DR SMART; SM00360; RRM; 2.
DR SMART; SM00547; ZnF_RBZ; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50174; G_PATCH; 1.
DR PROSITE; PS50102; RRM; 2.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS50199; ZF_RANBP2_2; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}; Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 100..180
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 183..212
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 233..317
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 683..713
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 780..826
FT /note="G-patch"
FT /evidence="ECO:0000259|PROSITE:PS50174"
FT REGION 1..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..568
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 652..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..99
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..548
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 552..568
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 852 AA; 94430 MW; A14BDA0A6A954B0C CRC64;
MGADKRISRT ERSGRYGSEQ SRDDPDWRDR RDQDRDHNSR RWSEERRDRY DGDRRGPRDS
PEQRERKRRN SDRSEDGYHS DGDYQEQDYR REPGDDRKSK TIMLGGLSSH TTEEDIRFAI
DQLEGPQPID VRLMKKRTGI SRGFAFVDFY HLQDATRWME TNQKLLVIQG KVVDMHYSHP
RNKYEDWLCN TCGLYNFRRR LKCFRCGAAK ADGEAGNAAG LPELQPTGDF YGDTIILRNI
APLTTVDTIL TALAPYANLS ANNIRLIKDK QTGQNRGFAF VQLSSPLEAS QLLTILQGLQ
PPLKMDGKTI GVDYAKSARK DLLLPDGNRV SAFSVASTAI AAAQWSSAQP QQSSDGMSEY
ACLQEGYAPL SQDYQTYYHQ GTAASTCQGN GILGAAPGVK LVPAAVVISQ SPQVYQPHII
APPAVQALPL AQQLEAKPQP GLAAVESVAL PALAVAAAQV NGASAVPAAG PAAGSTSGSL
PDTSTYQYDE SSGYYYDPQT GLYYDPNSQY YYNTQTQQYL YWDSEKQTYV PASGNINAGQ
NDKTANGSAG GNKEPKEKKE KPKSKTAQQI AKDMERWAKS LNKQKENFKS SFQPISQEER
KEAAAADAGF TLFEKKQAGL DRLMQEVARC AEEEALPISS ASSSKCGLVA AYSGDSDPEE
GVGGGESDGG DLSLDKLTDW KKMACLLCRR QFPNKEGLVR HQQLSDLHKK NLEVLRRSKM
SEAELEELER KETEQKYRDR AAERREKYGI PEPPVPKKKK FNQPAPVVNY EQPTKDGLTS
DNIGNKMLQA MGWKEGKGLG RNQQGITAPI EAQLRTKGAG LGTKGTNYTL SASDTYKDAV
RKAMFARFTE LE
//
