ID   A0A3B3WNT9_9TELE        Unreviewed;       605 AA.
AC   A0A3B3WNT9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Autophagy-related protein 16 domain-containing protein {ECO:0000259|Pfam:PF08614};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000004476.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000004476.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the WD repeat ATG16 family.
CC       {ECO:0000256|ARBA:ARBA00009271}.
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DR   RefSeq; XP_014836485.1; XM_014980999.1.
DR   RefSeq; XP_014836486.1; XM_014981000.1.
DR   AlphaFoldDB; A0A3B3WNT9; -.
DR   STRING; 48701.ENSPMEP00000004476; -.
DR   Ensembl; ENSPMET00000009125.1; ENSPMEP00000004476.1; ENSPMEG00000005792.1.
DR   GeneID; 106914296; -.
DR   KEGG; pmei:106914296; -.
DR   CTD; 55054; -.
DR   OrthoDB; 458014at2759; -.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0000045; P:autophagosome assembly; IEA:InterPro.
DR   CDD; cd22887; Atg16_CCD; 1.
DR   CDD; cd00200; WD40; 1.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR   InterPro; IPR045160; ATG16.
DR   InterPro; IPR013923; Autophagy-rel_prot_16_dom.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR19878; AUTOPHAGY PROTEIN 16-LIKE; 1.
DR   PANTHER; PTHR19878:SF6; AUTOPHAGY-RELATED PROTEIN 16-1; 1.
DR   Pfam; PF08614; ATG16; 1.
DR   Pfam; PF00400; WD40; 5.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 3.
DR   PROSITE; PS50082; WD_REPEATS_2; 5.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE   3: Inferred from homology;
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW   ProRule:PRU00221}.
FT   DOMAIN          13..202
FT                   /note="Autophagy-related protein 16"
FT                   /evidence="ECO:0000259|Pfam:PF08614"
FT   REPEAT          316..357
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          360..401
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          402..443
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          538..569
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          571..605
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          200..305
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        200..232
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        252..298
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   605 AA;  68078 MW;  E69CB81FD3C57213 CRC64;
     MAERRADCSW KRHISDQLKL RDRVQRHTFE EIVQQYNRLL EKSDLQAVLT ERYQIEKYDV
     QRGHEASSLD ASRSDSLHQE MSQMRIRHQE ELTELHKKRG ELAQTVIELN NQIQQKDREI
     QSNEARMLEY QQQIASLEGD CRDLRNSLQE LEMANQTLKD EYDALQITFS ALEEKLRKTS
     EDNQELVSRW MAEKALEANR LNAENEKDTR RRQAKLQKDL ADAAKEPLPI EQDDDIEVLA
     EDGGKGAGET SPNRPISRTA SRKTSQQPQG GLLDSISNIF GRRRSANSFG TSPETTEPPS
     GGCAEVRVPT TALHVFEAHD GEVNTVRFSP GSRLLATGGM DRRVKLWEVV AGRCEAKGAL
     TGSNAGITSI DFDSAGSYLL AASNDFASRI WTMDDYRLRH TLTGHSGKVL SARFLLDNAR
     IVSGSYDRTL KLWDLRSKVC MKTVFAGSSC NDIVCTEQCV MSGHFDKKVR FWDIRAESIV
     REMELLGRVT SLDLNHDRSE LLTCSRDDVL KIIDLRSNAI RQTFSAQGFK CGADWTRVTF
     SPDGSYVAGG SADGALYVWN VLTGKLDRTL DRNHSSAINS VSWSPSGTYV ASVEKGSRAI
     LWSDM
//