ID A0A3B3WPF0_9TELE Unreviewed; 149 AA.
AC A0A3B3WPF0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Relaxin-3 {ECO:0000256|ARBA:ARBA00040355};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000004688.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000004688.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBUNIT: Heterodimer of a B chain and an A chain linked by two
CC disulfide bonds. {ECO:0000256|ARBA:ARBA00011207}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC ECO:0000256|RuleBase:RU000406}.
CC -!- SIMILARITY: Belongs to the insulin family.
CC {ECO:0000256|ARBA:ARBA00009034, ECO:0000256|RuleBase:RU000406}.
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DR RefSeq; XP_014864299.1; XM_015008813.1.
DR AlphaFoldDB; A0A3B3WPF0; -.
DR STRING; 48701.ENSPMEP00000004688; -.
DR Ensembl; ENSPMET00000008748.1; ENSPMEP00000004688.1; ENSPMEG00000005990.1.
DR GeneID; 106930940; -.
DR KEGG; pmei:106930940; -.
DR CTD; 503864; -.
DR OrthoDB; 5353072at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR CDD; cd04365; IlGF_relaxin_like; 1.
DR InterPro; IPR016179; Insulin-like.
DR InterPro; IPR036438; Insulin-like_sf.
DR InterPro; IPR022353; Insulin_CS.
DR InterPro; IPR022352; Insulin_family.
DR PANTHER; PTHR20968; ILGF DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR20968:SF0; RELAXIN-3; 1.
DR Pfam; PF00049; Insulin; 1.
DR PRINTS; PR00276; INSULINFAMLY.
DR SMART; SM00078; IlGF; 1.
DR SUPFAM; SSF56994; Insulin-like; 1.
DR PROSITE; PS00262; INSULIN; 1.
PE 3: Inferred from homology;
KW Secreted {ECO:0000256|ARBA:ARBA00022525, ECO:0000256|RuleBase:RU000406};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..149
FT /note="Relaxin-3"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017382264"
FT DOMAIN 28..149
FT /note="Insulin-like"
FT /evidence="ECO:0000259|SMART:SM00078"
SQ SEQUENCE 149 AA; 16395 MW; 740A77F0C37756C4 CRC64;
MWKAVVMAVC LLVAGVGAQP MEDPTYGVKL CGREFIRAVI FTCGGSRWKR SLRSPDVSED
PFTSHQDESS EGLTSNFMVE NFLQTTKDLS FTPQNNPNGG FSRSTRSFIT DEILEALRKA
DRKGRDVVVG LSNACCKWGC SKSEISSLC
//
