ID A0A3B3WPV2_9TELE Unreviewed; 364 AA.
AC A0A3B3WPV2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Protein Wnt {ECO:0000256|RuleBase:RU003500};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000004684.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000004684.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Ligand for members of the frizzled family of seven
CC transmembrane receptors. {ECO:0000256|RuleBase:RU003500}.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix {ECO:0000256|ARBA:ARBA00004498, ECO:0000256|RuleBase:RU003500}.
CC -!- SIMILARITY: Belongs to the Wnt family. {ECO:0000256|ARBA:ARBA00005683,
CC ECO:0000256|RuleBase:RU003500}.
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DR RefSeq; XP_014825402.1; XM_014969916.1.
DR AlphaFoldDB; A0A3B3WPV2; -.
DR STRING; 48701.ENSPMEP00000004684; -.
DR Ensembl; ENSPMET00000008768.1; ENSPMEP00000004684.1; ENSPMEG00000005974.1.
DR GeneID; 106905229; -.
DR CTD; 791993; -.
DR OrthoDB; 2874082at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005102; F:signaling receptor binding; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd19336; Wnt_Wnt4; 1.
DR Gene3D; 3.30.2460.20; -; 1.
DR InterPro; IPR005817; Wnt.
DR InterPro; IPR043158; Wnt_C.
DR InterPro; IPR018161; Wnt_CS.
DR PANTHER; PTHR12027:SF104; PROTEIN WNT; 1.
DR PANTHER; PTHR12027; WNT RELATED; 1.
DR Pfam; PF00110; wnt; 1.
DR PRINTS; PR01349; WNTPROTEIN.
DR SMART; SM00097; WNT1; 1.
DR PROSITE; PS00246; WNT1; 1.
PE 3: Inferred from homology;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473,
KW ECO:0000256|RuleBase:RU003500};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Extracellular matrix {ECO:0000256|ARBA:ARBA00022530};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP};
KW Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687,
KW ECO:0000256|RuleBase:RU003500}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..364
FT /note="Protein Wnt"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017416726"
SQ SEQUENCE 364 AA; 39740 MW; 3EAB664F950D102D CRC64;
MPTVSPVNLS APLLLLLLLL LLLLCTTHTT MATNWLSLAR LPRSRAVSGA APCARLRGLT
PGQVGVCRAR GEVMESVRKA AEMVIEECQH QFRNRRWNCS TTPRGINVFG RVMNQGTREA
AFVHALSSAA VAVAVTRACT RGELERCGCD RKVRGVSPEG FQWSGCSDNL SYGVAFSQTF
VDEPERAKGL SAGRPLMNLH NNEAGRKAIL HNMQVECKCH GVSGSCELKT CWKVMPPFRR
VGVVLKERFD GATEVRLTRI GSRPALLPRD PYVKPPAARD LVYVAPSPDF CHLDPDNGIP
GTAGRRCNGT SRLAPDGCEL VCCGPGYRAG RAEVVQRCSC KFSWCCSVRC QQCKNTVTIH
TCRV
//
