ID A0A3B3WQQ3_9TELE Unreviewed; 1258 AA.
AC A0A3B3WQQ3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPMEP00000005131.1};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000005131.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000005131.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_014849561.1; XM_014994075.1.
DR AlphaFoldDB; A0A3B3WQQ3; -.
DR STRING; 48701.ENSPMEP00000005131; -.
DR Ensembl; ENSPMET00000008013.1; ENSPMEP00000005131.1; ENSPMEG00000006468.1.
DR GeneID; 106922006; -.
DR KEGG; pmei:106922006; -.
DR CTD; 768131; -.
DR OrthoDB; 2877903at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0140938; F:histone H3 methyltransferase activity; IEA:UniProt.
DR GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd01395; HMT_MBD; 1.
DR CDD; cd10517; SET_SETDB1; 1.
DR CDD; cd20382; Tudor_SETDB1_rpt1; 1.
DR CDD; cd21181; Tudor_SETDB1_rpt2; 1.
DR Gene3D; 2.30.30.140; -; 3.
DR Gene3D; 2.170.270.10; SET domain; 2.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR040880; DUF5604.
DR InterPro; IPR025796; Hist-Lys_N-MeTrfase_SETDB1.
DR InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR007728; Pre-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR047232; SETDB1/2-like_MBD.
DR InterPro; IPR002999; Tudor.
DR InterPro; IPR041292; Tudor_4.
DR InterPro; IPR041291; TUDOR_5.
DR PANTHER; PTHR46024; HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS; 1.
DR PANTHER; PTHR46024:SF2; HISTONE-LYSINE N-METHYLTRANSFERASE SETDB1; 1.
DR Pfam; PF18300; DUF5604; 1.
DR Pfam; PF01429; MBD; 1.
DR Pfam; PF05033; Pre-SET; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF18358; Tudor_4; 1.
DR Pfam; PF18359; Tudor_5; 1.
DR SMART; SM00391; MBD; 1.
DR SMART; SM00468; PreSET; 1.
DR SMART; SM00317; SET; 1.
DR SMART; SM00333; TUDOR; 2.
DR SUPFAM; SSF81995; beta-sandwich domain of Sec23/24; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50867; PRE_SET; 1.
DR PROSITE; PS51573; SAM_MT43_SUVAR39_1; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 777..850
FT /note="Pre-SET"
FT /evidence="ECO:0000259|PROSITE:PS50867"
FT DOMAIN 853..1233
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 1242..1258
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 94..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..527
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 568..587
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 945..1112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1125..1161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 31..75
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 986..1022
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1023..1038
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1044..1058
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1059..1078
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1258 AA; 139361 MW; C2F455396420F5CC CRC64;
MESGDGMEVD GWDPSLEDEL GVSLDDLKKW IEEAVEQSEA VKKKKAQLIE LEEWVEQKEK
EEAKTEKLLN DANQSVLECE KLVRAAYENN GLVYRESSSD DEGGGGGGLP SEVIEIDDDD
DDDVIAVGCL VPPKTQAPSK DPTLNEASAV LQKTTQQVQK LVQIVTKPSS ASPLIRTAVQ
SVVQPGVQST TPAIFVSQAP SHQTMTQTQP NPNIKEDELK VGMNILGKKR TKTWHKGNLV
AINPVGNGVF KYKVRFDKGK SLLSGNHVAF DYNPTLESLY VGARVVAKYK DGNLVWLYAG
IVAEMPNNKN RMRFLIFFDD GYASYVILPE LYPVCRPLKR TWEDIEDASC RDFIEEYISA
YPSRPMVLLK VGQIIKTEWE GTWWKSKVEE VDSSLVKILF LDDKRSEWIY RGSTRLEPMF
NLKLASANTQ EKKLAGHQRT RPNMGALRSK GPVVQYTGVE HVGVSPAKPP QTTQSQPPAM
TLIQQLQQRP QPQLLQQVQL SQQTQQTLQP QAQQTQQTPQ PSPAAQFQRI ENKHQMAKKS
TSNFIPGVGG THASKILQAA SANASNLSVG KVQSTPNTPT SSFTPPYQRQ TTALAPPPSI
VTHAMATIPQ QPSYRAPTDR IFYLAHTCQP ACLNRVRPAK SDLHRGKNPL LTPLLYDFRR
MTGRRKVNRK MSFHVIYKAP CGLCLRNMGE IQNYLFQTRC DFIFLEMFCL DPYVLVDRPF
QPQRPFYYIP DITSGKEDIP LSCVNEIDTT PPPNVKYSKE RIPEDGVFIN TSSDFLVGCE
CTDGCKDKSK CSCHQLTLQA SGCTPGGQIN QSAGYSYKRL EECLPTGIYE CNKRCKCCAQ
MCTNRLVQHG LQVRLQLFKT QNKGWGIRCL DDIAKGSFVC IYAGKILTDD FADKEGLEMG
DEYFANLDHI ESVENFKEGY ESEAHCSDSE GSGVDVSRMK IQPSALVSSG AARKKAQSSS
SSDDSNDEEE KDSKSEDESD SSDDTFVKDN YYTPSSVWRS YTTRGQAKGN KEGSQDSKDG
LSVSAKGQDD EKPPSMPEET GKSKVASWLT SQGLKKETGD NKSQIKTEQS KKQDVMTLSD
SDDVQTISSG SEDNKDREKA APASVSGVTK KQVAVKSTRG IALKNSHSMM VKPSGGGVGP
SVQGSKPGHQ GQPGGGAENA PKNTRLFFDG EESCYIIDAK LEGNLGRYLN HSCSPNLFVQ
NVFVDTHDLR FPWVAFFASK RIRAGTELTW DYNYEVGSVE GKELLCCCGS TECRGRLL
//
