ID   A0A3B3WY08_9TELE        Unreviewed;       568 AA.
AC   A0A3B3WY08;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Bloodthirsty-related gene family, member 12 {ECO:0008006|Google:ProtNLM};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000007638.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000007638.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   RefSeq; XP_014841035.1; XM_014985549.1.
DR   AlphaFoldDB; A0A3B3WY08; -.
DR   STRING; 48701.ENSPMEP00000007638; -.
DR   Ensembl; ENSPMET00000003801.1; ENSPMEP00000007638.1; ENSPMEG00000009311.1.
DR   GeneID; 106916932; -.
DR   KEGG; pmei:106916932; -.
DR   CTD; 767681; -.
DR   OrthoDB; 4218101at2759; -.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0002376; P:immune system process; IEA:UniProtKB-KW.
DR   CDD; cd19802; Bbox1_TRIM8-like; 1.
DR   CDD; cd19769; Bbox2_TRIM16-like; 1.
DR   CDD; cd13733; SPRY_PRY_C-I_1; 1.
DR   Gene3D; 2.60.120.920; -; 1.
DR   Gene3D; 4.10.830.40; -; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR043136; B30.2/SPRY_sf.
DR   InterPro; IPR003879; Butyrophylin_SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR006574; PRY.
DR   InterPro; IPR003877; SPRY_dom.
DR   InterPro; IPR027370; Znf-RING_euk.
DR   InterPro; IPR000315; Znf_B-box.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR25465:SF34; TRIPARTITE MOTIF-CONTAINING 80; 1.
DR   Pfam; PF13765; PRY; 1.
DR   Pfam; PF00622; SPRY; 1.
DR   Pfam; PF00643; zf-B_box; 1.
DR   Pfam; PF13445; zf-RING_UBOX; 1.
DR   PRINTS; PR01407; BUTYPHLNCDUF.
DR   SMART; SM00336; BBOX; 1.
DR   SMART; SM00589; PRY; 1.
DR   SMART; SM00184; RING; 1.
DR   SMART; SM00449; SPRY; 1.
DR   SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR   SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS50188; B302_SPRY; 1.
DR   PROSITE; PS50119; ZF_BBOX; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Immunity {ECO:0000256|ARBA:ARBA00022859};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00024}.
FT   DOMAIN          18..58
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   DOMAIN          173..213
FT                   /note="B box-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50119"
FT   DOMAIN          372..567
FT                   /note="B30.2/SPRY"
FT                   /evidence="ECO:0000259|PROSITE:PS50188"
FT   REGION          86..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          286..320
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   568 AA;  64009 MW;  5058FA3B68286112 CRC64;
     MSINSPSGRA LTEDQFTCSI CLEIFVEPVS TPCGHSFCKA CLQGYWNHSK KFLCPMCKKS
     YSRRPEMSVN RVLAEISSQF QGLVVSGGAS GSPSRGGSMT MSSDPGHSSS PAQDTGEFAQ
     PGDVPCDACI GRKLKALKSC VNCPGSYCEA HLRHHKKVKT LTSHCLIEPT FYLEEKICKK
     HERLLEVYCC TDHTCICKSC AEATHKSHDI ISVDQEFKKK MTNLGKKRSV LKNLIKERAK
     KLEEIKQSIK VIKASSQKEL EDSWQVYGAL QKLVEQSQAE MVELITARER EAERHAQEQA
     RSLENELSQL RRRSNELEAH AHTKDKVVFL QNLATLSHSP EYTDWSGVSI NTDIYLGTLR
     SSVSGLIEKF QDELKKLYAK EFRKVQNYAS EVVLDPSTAQ KNLVVTHEGQ QVKYEEHKVS
     HSEGPKRFNP ALFVLGRESI HSGRHYWEVE VGRKTAWTLG VARATARRKG EIKLNPEGGY
     WCLWLKNGEV KALAETRLPL ALMSHPSKVG LFLDYEAGQL SFYDVKARQH LYTFMDKFNE
     SVYPIFSPCL SQDGKNNSPL IITQVKHT
//