ID   A0A3B3WYZ3_9TELE        Unreviewed;       746 AA.
AC   A0A3B3WYZ3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=FH2 domain-containing protein {ECO:0000259|PROSITE:PS51444};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000007963.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000007963.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3WYZ3; -.
DR   STRING; 48701.ENSPMEP00000007963; -.
DR   Ensembl; ENSPMET00000003253.1; ENSPMEP00000007963.1; ENSPMEG00000009863.1.
DR   Proteomes; UP000261480; Unplaced.
DR   Gene3D; 1.20.1160.20; -; 1.
DR   Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR   InterPro; IPR015425; FH2_Formin.
DR   InterPro; IPR042201; FH2_Formin_sf.
DR   PANTHER; PTHR45725:SF12; DELPHILIN-RELATED; 1.
DR   PANTHER; PTHR45725; FORMIN HOMOLOGY 2 FAMILY MEMBER; 1.
DR   Pfam; PF02181; FH2; 1.
DR   SMART; SM00498; FH2; 1.
DR   SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR   PROSITE; PS51444; FH2; 1.
PE   4: Predicted;
FT   DOMAIN          361..746
FT                   /note="FH2"
FT                   /evidence="ECO:0000259|PROSITE:PS51444"
FT   REGION          156..221
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          234..286
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          323..374
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          726..746
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        234..248
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        249..263
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        350..374
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   746 AA;  82952 MW;  8DEF97D2BA157C8D CRC64;
     VSGWSCSHEK VVSMLQGSGA VPTLVVEDGP SDFSSDQTDP EESPALSSLQ WVAEILPPSI
     KVQGRTFSQQ LDHLLTIQER YTVCKALETF FQHRNLDSLI VDVFPVLDTP AKQLIWQFIH
     QLLTYDEQER CQSKLSACFS VLPALLRASR ASRAHGRVSP RSASGIHVDE CGSPEERQSG
     DGTSFPESPD LSHVAASGRS AAGRDGVSLC PTGSRKSGLS LSWKEPLPSA VYQVQHQSSV
     ESNPYVSLES PPASPPPPRP ASGPNTLTRR RKLFTFSRPP RSRDTDKFLD ALSEQLGHRV
     TLVDDNDYEE VRGRSHRGTL LLRKGAEPQG NSLTLPTSMG VAFRPRRLSS GSSAERSSSS
     GDEDAPSPSS SSGCDWNRSV CFQLRENSDY DKLSDMVKYL DLDLHFGTQR RPKPAFLPEN
     LKKKDVVEIL SHKKAYNASI LMAHLKLSPD ELRQVLLDLS TDRLEPAHIK QLLLYAPDQD
     EVQQYQRFQQ DPAKLSEPDQ FIFQMLTVPE YKTRLRGLLF KTTLQERAEE MKAAFDYIYK
     ASVELKSSRK LAKILEFVLA MGNYLNNGQP KSHRTTSFKI NFLTELSTTK TVDGKSTFLH
     ILAKSLSQHF PELLSFPREL LTVPLAAKVN QRAVTTELSE LHAAAQDIRT ACQKLPASAD
     DHFASVMSSF LENSHPALQS LESLQSRAMA EFSEVASFFG EDSQSTSTDS FFGIFAEFMS
     KFERALSETQ SPENPRSPRL SSPLAW
//