ID   A0A3B3X121_9TELE        Unreviewed;       420 AA.
AC   A0A3B3X121;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Acyl-CoA thioesterase 21 {ECO:0008006|Google:ProtNLM};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000008708.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000008708.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC       {ECO:0000256|ARBA:ARBA00006538}.
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DR   RefSeq; XP_014869634.1; XM_015014148.1.
DR   RefSeq; XP_014869635.1; XM_015014149.1.
DR   RefSeq; XP_014869636.1; XM_015014150.1.
DR   RefSeq; XP_014869637.1; XM_015014151.1.
DR   AlphaFoldDB; A0A3B3X121; -.
DR   STRING; 48701.ENSPMEP00000008708; -.
DR   Ensembl; ENSPMET00000002001.1; ENSPMEP00000008708.1; ENSPMEG00000010468.1.
DR   GeneID; 106934326; -.
DR   KEGG; pmei:106934326; -.
DR   OrthoDB; 5356064at2759; -.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR   InterPro; IPR014940; BAAT_C.
DR   InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR   InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR   PANTHER; PTHR10824:SF17; ACYL-COENZYME A THIOESTERASE 6; 1.
DR   PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR   Pfam; PF08840; BAAT_C; 1.
DR   Pfam; PF04775; Bile_Hydr_Trans; 1.
DR   PIRSF; PIRSF016521; Acyl-CoA_hydro; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
FT   DOMAIN          18..139
FT                   /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT                   acid N-acetyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF04775"
FT   DOMAIN          201..410
FT                   /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08840"
FT   ACT_SITE        230
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        325
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        359
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ   SEQUENCE   420 AA;  46394 MW;  FFF73033AF0A7D75 CRC64;
     MSNQVRLRLL PTARCLFDEP IQLKVAGLRS KQMVTMRARS TDEKGVVFSS SATYRADGSG
     EIDLSRDASL SGNYVGVEPM GLLWSMRPDI LHKRFQKTNS LNPHVVNFSV HEEEGGMLAE
     VKNERFLMGD GVSRVPVKQG NIRGVLFTPP GEGPFPAVLD LYTFGGGLSE KRAALLASRG
     FLVLTVALYG HDDLPKNIKE VHLDYFEESI KFLKNQDKAG SNGVGVISLS KSGDLALSVA
     SYLPGVQAVI WINGCSANVA FPLYYKNRQI LSALKFDMNK VISTESGAII TKYGMHDPLK
     EENKASLVPI ERASGRFLFV ASEDDLNWDS KAYMNAMVDR LKRHGKENFE SVSYPGAGHY
     LEPPFGPYCP SSFHAVTGVP VLWGGEPKAH AAAEVHLWRK IQEFFRTHLS CDKIKIKSKL
//