ID A0A3B3X5H1_9TELE Unreviewed; 1007 AA.
AC A0A3B3X5H1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=PHD finger protein 12b {ECO:0008006|Google:ProtNLM};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000010287.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000010287.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_014868093.1; XM_015012607.1.
DR AlphaFoldDB; A0A3B3X5H1; -.
DR STRING; 48701.ENSPMEP00000010287; -.
DR Ensembl; ENSPMET00000030933.1; ENSPMEP00000010287.1; ENSPMEG00000012209.1.
DR GeneID; 106933394; -.
DR KEGG; pmei:106933394; -.
DR CTD; 57649; -.
DR OrthoDB; 5491843at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd22703; FHA_PHF12; 1.
DR CDD; cd15533; PHD1_PHF12; 1.
DR CDD; cd15534; PHD2_PHF12_Rco1; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.20.60; PHD finger protein 12; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR031966; PHF12_MRG-bd.
DR InterPro; IPR038098; PHF12_MRG-bd_sf.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46309; PHD FINGER PROTEIN 12; 1.
DR PANTHER; PTHR46309:SF1; PHD FINGER PROTEIN 12; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00628; PHD; 2.
DR Pfam; PF16737; PHF12_MRG_bd; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 56..105
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 292..342
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 787..841
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT REGION 106..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 488..521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 945..1007
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 117..132
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..210
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 613..642
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1007 AA; 109541 MW; 090EB8E61D4D43A3 CRC64;
MWDKMETPTI VYDLDTSGGL MEQIQTLLAP PKSEDVEKRS RKLVRDVRRS GRATNHDTCD
SCREGGDLLC CDHCPAAFHL QCCNPPLSEE MLPSGEWMCH RCNMRKKKRE QKSEQTNGFP
DRSSTKRSTS PTGELEVGPG PLRLDGLPPG AGAAGPGLRV AQVRLLDRRT SSRPSSRPGT
PTSNTSSTPT PSEEQNDGEE EAADPEDDVQ AVEPDGAALS VPAPRLLKRP FQLLIAAAME
RNPTQFQLPS ELTCTTALPG SSKRRRKEEL LGKPFRRPQH ELDPNGLVPL PVKVCFSCNR
SCRLAPLIQC DYCPLLFHMD CLDPPLTALP AGKWMCPNHV EHLVLNQRSL SLSSRCQLFD
QFQDRISQHA VRLNFLRRVH RQNAPNRRTS YQQNKKTIKV PDAIKSQYQN PPPMLLPAGV
HQVELVCSGL PHHQPAKHLT TELEQEEWLQ DIIALQCSIM RHLSISQKVR SATPTDLPPE
CERKRTCVTS EEMKSQVAEG RTSPEPCSKP CGAPEPPQEA HIARDASAEL GGCKCSMAPC
PKCRKPNGPL AELHPPKANG PLDCNSASDT CRPPDPQHRL KTRTNSPLDS AVPSGLMNHI
GTDTVKKDPE SATEACAQNN RPLVWPQSSQ QNHRSQMELQ ELCLSSDEKP PSHLPDTPLK
GSYKQTSSKH GPDSAPPDVK AGPGLMDCLL PSALSSINTL SSCRNSARDV GGIELDKLDE
ETIRFLAYQR IQQLFPPKAL SSPPLLTPGV SSNLPAPHLD SQKVQARAVF CPLAGRGQTV
SMCYRTLYIG SGADMDVCLT NYGHCSYISG KHACIFYDEN TKHYELLNYS EHGTTVDNVL
YSCDFSEKVL PAAPSSLVAR VQGLIRRSKK REEDKVVGVM PAGGVMSSQP QGGAAACSCK
VSGSSLIGGS GAGWEGTALL HHGSYIKLGC LQFVFSITEF ADEEPPVAPP AGCTGSSSQS
SAPASTSTPP RPPPSTAMAS SPSSQDEADT ELAPLHQVPV LRYNSVP
//
