ID A0A3B3X5J9_9TELE Unreviewed; 548 AA.
AC A0A3B3X5J9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000010219.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000010219.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3X5J9; -.
DR Ensembl; ENSPMET00000017011.1; ENSPMEP00000010219.1; ENSPMEG00000012522.1.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 1.20.5.30; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036337; Matrilin_cc_sf.
DR InterPro; IPR019466; Matrilin_coiled-coil_trimer.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF14; MATRILIN-4; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF14670; FXa_inhibition; 2.
DR Pfam; PF10393; Matrilin_ccoil; 1.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 3.
DR SMART; SM01279; Matrilin_ccoil; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF58002; Chicken cartilage matrix protein; 1.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536}.
FT DOMAIN 14..190
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 327..502
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
SQ SEQUENCE 548 AA; 60651 MW; 6AA2512872CB9371 CRC64;
PHGPNQKCKS GPVDLVFLID SSRSVRPHEF ETMRKFLIDI LNTLDIGLDT TRVGVVQYSS
QVRSEFSLKT HSKLENMVKA INEIVPLAQG TMTGLAIRYL MNEAFSPGQG DRPKVPNVAV
IVTDGRPQDR VAEVAAEARE RGIEIYAVGV ARADMTSLRA MASPPFEDHV FLVERFDLIY
QFGLQFQDKL CAIDLSIDLC AEGKHDCGHV CVNMGPGIFT CDCKKGYRLN EDEKSCSAID
LCAEGKHDCE QICISTPGVF TCDCNKGFKL NRDKRTCTNM DMCNTVKHGC DYQCVNTPGS
YHCICPEGQL LQDDGKTCGT CKSANIDLVL LIDGSKSVRP QNFELVKKFV NQVVDSLDVS
AHGTRVGLVQ YSSRVRTEFP LNMYHTAEDI KAAVMKVDYM EKGTMTGLAL KHMLEYSFSE
AEGARPASRN IPRIGLVFTD GRSQDDISEY AKKAKEAGIT MYAVGVGKAV EDELREIASD
PVEKHFYYTT DFSAINTIAD NLKLNVCPAE SQGEVEVKDP CACENLVEFQ QATMNSLDQF
TQKHILSK
//
