ID A0A3B3X5M7_9TELE Unreviewed; 914 AA.
AC A0A3B3X5M7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Exostosin GT47 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000010275.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000010275.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004648}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004648}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 47 family.
CC {ECO:0000256|ARBA:ARBA00010271}.
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DR RefSeq; XP_014833606.1; XM_014978120.1.
DR AlphaFoldDB; A0A3B3X5M7; -.
DR STRING; 48701.ENSPMEP00000010275; -.
DR Ensembl; ENSPMET00000017101.1; ENSPMEP00000010275.1; ENSPMEG00000012225.1.
DR GeneID; 106911334; -.
DR KEGG; pmei:106911334; -.
DR CTD; 2137; -.
DR OrthoDB; 1220028at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR InterPro; IPR004263; Exostosin.
DR InterPro; IPR040911; Exostosin_GT47.
DR InterPro; IPR015338; GT64.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR48261; ACETYLGLUCOSAMINYLTRANSFERASE; 1.
DR PANTHER; PTHR48261:SF2; EXOSTOSIN-1-LIKE; 1.
DR Pfam; PF03016; Exostosin; 1.
DR Pfam; PF09258; Glyco_transf_64; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 22..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 185..495
FT /note="Exostosin GT47"
FT /evidence="ECO:0000259|Pfam:PF03016"
FT DOMAIN 658..899
FT /note="Glycosyl transferase 64"
FT /evidence="ECO:0000259|Pfam:PF09258"
FT COILED 72..141
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 914 AA; 103478 MW; 2F09A5B4F10DCD4B CRC64;
MQRNGGGVGG GGQTWVLRRV RLTWLSFMLF FILVFFPLIA HYYLTTIDEA GGPDKRIFGP
RPGGELCEAK HVQDLCRIRE SVSEELLQLE AKRQELNGEI ARLNLRIEAC KRSIDSAKQD
LLQLKNVISQ TEHSYKELMA QNQPKLSLPV RLLPDKEDPG LPPPKSPRSC RLRSCFDYAR
CPLTSGFPVY VYDTSSYAWG NNLDPLVKQA FAASVKSNIY VTDNPSIACL YLVLVGEILE
SSPLPSPSEL EKQLKALPYW RSDGHNHVLV HFSRKSMTQN FLYNVSTGRA AVAQSTFLEQ
QYREGFDLVV SPLVHALSEP NFLEVPPQVP VKRKYLFTFQ GERVESLRSS LQEAPPQSFE
EELQGDPPAD YDDRIIGTLK AVQDSHLDQV LVEFTCKNPK PSLPTEWALC GEREDRLEVL
KASTFALVIA PGDGQLVASA GCGMRLFEAL EVGAIPVMLG DHSRLPYHQF IRWTEAAIIV
PKPRVTELHF LLRSLSDNDM LAMRRQGRFL WETYFSTSEN VLNTILASIR TSIQVPAAPI
KDEPAHEIPH KAGKLAGTDA NLADNGDLDL GPVETEPPYA SPCFLRNFTY TAADTYRSWN
RAPGPFHLFP HTPLDPVLPS EAKFLGSGTG FRPIGGGSGG SGKEFQAALG GNVPREQFTV
VMLTYEREEV LMNSLERLNG LPYLNKVVVV WNSPKPPSDD LLWPDIGLPI VVVRTEKNSL
NNRFLPWDVV ETEAILSIDD DAHLRHDEIM FGFRVWREAR DRIVGFPGRY HAWDVNHQSW
LYNSNYSCEL SMVLTGAAFF HKYYAYLYSY VMPQAIRDMV DEYINCEDIA MNFLVSHITR
KPPIKVTSRW TFRCPGCPQA LSHDDSHFHE RHKCINFFVK VYGYMPLLYT QFRVDSVLFK
TRLPHDKTKC FKFI
//
