ID   A0A3B3XAR4_9TELE        Unreviewed;      1240 AA.
AC   A0A3B3XAR4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000012147.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000012147.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC       matrix {ECO:0000256|ARBA:ARBA00004498}.
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DR   RefSeq; XP_014855337.1; XM_014999851.1.
DR   AlphaFoldDB; A0A3B3XAR4; -.
DR   STRING; 48701.ENSPMEP00000012147; -.
DR   Ensembl; ENSPMET00000019476.1; ENSPMEP00000012147.1; ENSPMEG00000000546.1.
DR   GeneID; 106925475; -.
DR   KEGG; pmei:106925475; -.
DR   CTD; 148113; -.
DR   OrthoDB; 5383253at2759; -.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 2.
DR   InterPro; IPR008969; CarboxyPept-like_regulatory.
DR   InterPro; IPR039675; CILP1/CILP2.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR000884; TSP1_rpt.
DR   InterPro; IPR036383; TSP1_rpt_sf.
DR   InterPro; IPR025155; WxxW_domain.
DR   PANTHER; PTHR15031:SF7; CARTILAGE INTERMEDIATE LAYER PROTEIN 2; 1.
DR   PANTHER; PTHR15031; CARTILAGE INTERMEDIATE LAYER PROTEIN CLIP; 1.
DR   Pfam; PF13927; Ig_3; 1.
DR   Pfam; PF13330; Mucin2_WxxW; 1.
DR   Pfam; PF00090; TSP_1; 2.
DR   SMART; SM00409; IG; 1.
DR   SMART; SM00408; IGc2; 1.
DR   SMART; SM00209; TSP1; 2.
DR   SUPFAM; SSF49464; Carboxypeptidase regulatory domain-like; 1.
DR   SUPFAM; SSF48726; Immunoglobulin; 1.
DR   SUPFAM; SSF82895; TSP-1 type 1 repeat; 2.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS50092; TSP1; 2.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00022989};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022989};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..1240
FT                   /note="Ig-like domain-containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017456937"
FT   DOMAIN          349..433
FT                   /note="Ig-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50835"
FT   REGION          1199..1240
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1199..1222
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1240 AA;  138609 MW;  3BE3129B8D77C566 CRC64;
     MFFFYFFTLC AGLLWTRNPS DRSKRVVFNT FTDSQTTGVT EWTSWFNIDH PGGNGDYERL
     EAIRFYYRER VCARPTAMEA RTTDWVAAAD TGEVVHSSLE KGFWCINKEQ PYGRVCSNYH
     VRFQCPPVQS YWTDWSEWGP CSTTVCNDVG IQVRQRKCVS AQPMPLLFVP ACIGHHAERR
     ECSAPPCAAK WSPWGSWGSC SVTCGGGRRT RRRTCVRTSE TVHCPGRPAE VQKCGRSRCP
     ATCKLTCSEG HPSEDCSICV CEGHMLFGDI QTVTGVPVAG ASVALTSHPK VIRTLTDVKG
     QFTLSGVCSS SSTSIAINKE KFVPAVVSAS SNATGISWLR AVLTSAEKPY IVKHPEDKVR
     YEGGRALLCC SATGSPAPDK YYWYHNGTLL DKNMYKYGND LVLRDLKLEQ SGEYYCKTSN
     AAGSIKSSPA HLTVIANGSP ACNATPETHL IRLPMDCVQP GTHSKYYNAG RCPHNKCPGS
     LDFDMRCRDG AGFCCGVQEM ESRNIDCGTY KLPIRAVKQC SCQKCVQPTV LVRGRVVAAD
     NDEPLRFGHI YIGKDRVGTT GYQGGFTLQI TPDTQRLVVN FVDPTQTYID TPKVFIFDKK
     SGSIYHNVKV MRKQTPVDIN PGETNFIDLG EIKGEDPIGQ LVIPPHSFHK DNGEIYEGTV
     KASVTFIDPR NITTAAAAPG DLNFVDEEGD MLPLRTYGMF SVDFRDETSK EVLGTGAVQV
     LLDTQHVKMQ EHIPTMKLWS LNPDTGVWEE ESDFSYSATT AGSHGRSKRE ERTFLIGNME
     IRERRLFNLD VPENRRCYVK VRAYMSEKFL PTEQLEGVVI SLINLEPKPG YSSNPRAWGR
     FDSVLTGPNG ACLPAFCDAM RPDAYTAYVT AILGGEELEA APSSPKMNPN IIGVSQPYLD
     KLDYQRSDHE DPALKKTAFR INLAKPNQNN FDETNGPIYP YQNLLACENA PVDANHFRFF
     RVEKDKYEYN VVPFEENDLT TWTGDYLSWW PNPQEFRACF IKVKIQGQKE VMVRSRNLGG
     THAETRGKLY GIRDIRSTRD MREANTSAAC VEFKCSGMLF DQAEVDRSLI SVIPQGSCRR
     ISTNGLLQEY LIKHPPVAQN NESHAFTMLA PVDPLGHNYG IYTVTDQNPR VAKEIAIGRC
     FDGTSDGFSR EMKSDYGVAL TFSCPEKKIN RESLFQRLQT NPGQTLSQMA RDMREVEGLQ
     VQRSSTQVVA FPSEQRGRTQ SRRASSATRR RASMRAQQRQ
//