ID A0A3B3XBL4_9TELE Unreviewed; 383 AA.
AC A0A3B3XBL4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=SH2 domain-containing protein {ECO:0000259|PROSITE:PS50001};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000012354.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000012354.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR RefSeq; XP_014850977.1; XM_014995491.1.
DR AlphaFoldDB; A0A3B3XBL4; -.
DR Ensembl; ENSPMET00000019760.1; ENSPMEP00000012354.1; ENSPMEG00000014531.1.
DR GeneID; 106922793; -.
DR CTD; 561247; -.
DR OrthoDB; 2963819at2759; -.
DR Proteomes; UP000261480; Unplaced.
DR CDD; cd09945; SH2_SHB_SHD_SHE_SHF_like; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR PANTHER; PTHR15127; HEAVYWEIGHT, ISOFORM A; 1.
DR PANTHER; PTHR15127:SF33; SH2 DOMAIN-CONTAINING ADAPTER PROTEIN D; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 283..378
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 42..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 85..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..212
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..185
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..212
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 383 AA; 43019 MW; ED3E924CDDAA2BF8 CRC64;
MAKWLKDYLN LGSRRDPPQP PRPDYTESEI LRAYRAQKEL DFEDPYQHSE KEHQNGGFGS
CTTTVSLPSF PAFGSVVSDG VEVVPSAPAA SDGETDYSDP FDARPNPRGR PNWELKSAPT
DCCSYMEPFE AQRIIADLQH TAMTNRSPSG DGGQLYDNPY EEKSRHQHRA APPAQQQQQQ
KSDAGAALMD SRESRLPQDD ERPADEYDQP WEWKKDNISK ALAVQFEGAE RERSRAQPEH
TRFAKTGSAS SACDATTLRL VGDTPPLLGE RVDPSLPLEK QVWYHGALSR SEAESLLTLC
KESSYLVRKS QTCQNDYSLS LRSCKGFMHM KFTQSADGRY VLGENSPPFC TIPEVIHYYT
THKLPIRGAE HMSLLYPVIV QTL
//
