ID   A0A3B3XCD2_9TELE        Unreviewed;       695 AA.
AC   A0A3B3XCD2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Anoctamin {ECO:0000256|RuleBase:RU280814};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000012722.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000012722.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU280814}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU280814}.
CC   -!- SIMILARITY: Belongs to the anoctamin family.
CC       {ECO:0000256|ARBA:ARBA00009671, ECO:0000256|RuleBase:RU280814}.
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DR   AlphaFoldDB; A0A3B3XCD2; -.
DR   STRING; 48701.ENSPMEP00000012722; -.
DR   Ensembl; ENSPMET00000020230.1; ENSPMEP00000012722.1; ENSPMEG00000015014.1.
DR   Proteomes; UP000261480; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   InterPro; IPR032394; Anoct_dimer.
DR   InterPro; IPR007632; Anoctamin.
DR   InterPro; IPR049452; Anoctamin_TM.
DR   PANTHER; PTHR12308; ANOCTAMIN; 1.
DR   PANTHER; PTHR12308:SF20; ANOCTAMIN-2; 1.
DR   Pfam; PF16178; Anoct_dimer; 1.
DR   Pfam; PF04547; Anoctamin; 1.
PE   3: Inferred from homology;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          8..50
FT                   /note="Anoctamin dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF16178"
FT   DOMAIN          53..625
FT                   /note="Anoctamin transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF04547"
SQ   SEQUENCE   695 AA;  80225 MW;  F2E3E05C88D2797A CRC64;
     MPLLSFPGIS TLIAKGVYDA AFPLHDVSVS REVLFEEWAR YSAFYKYQPI DLVRKYFGEK
     IGLYFAWLGV YTQLLIPASI VGIIVFGYGV ATVDTNIPSL EMCDERLNFT MCPLCDGACD
     YWHLSTACGT ARASHLFDNP ATVFFAIFMS LWAVLFLEHW KRRQISLSFS WDLTGIEEDE
     EHPRPKYETI LLEKRQRNTN AVLYTVHFLD IYHTLTNCQS IFFSLCCQFG LTFSAVFGVI
     IYRITISALM AMSPDPEIKS NVRVTVTATA VIINLVVILI LDEIYGTVAL WLTELEIPKT
     ETNFEERLIL KAFLLKFMNA YAPIFYVAFF KGRFAGRPGS YVYVFNDYRM EECAPGGCLI
     ELCIQLSIIM LGKQLIQNNI FEIGIPKLKK LIRTLKEKEP TQKEKDEERP PRQWNLDYAL
     VPFEGLTPEY MEMIIQFGFV SLFVASFPLA PLFALLNNVI EIRLDARKFV TELRRPVAAR
     AKDIGIWYNI LSGMGKLSVI INAFVIAFTS DFIPRLVYQY MYSQTGTMHG FIDHTLSFFN
     VSNFKPGTAP HSSDHGDITV CRYKDYREPP WSSDAYQFSK QYWSVLSARL AFVILFQNLV
     MFLSLMVAWV IPDVPKTIVE QLKREKKLLV DLFLQEEKEK FQLIQTRPLF WTSLCPESLG
     SRLLRNIRLL EEWIFKQLDL ILPRRYHLAV TYVML
//