ID   A0A3B3XE65_9TELE        Unreviewed;       575 AA.
AC   A0A3B3XE65;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=VWFD domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Poecilia mexicana.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC   Poecilia.
OX   NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000013258.1, ECO:0000313|Proteomes:UP000261480};
RN   [1] {ECO:0000313|Ensembl:ENSPMEP00000013258.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3B3XE65; -.
DR   STRING; 48701.ENSPMEP00000013258; -.
DR   Ensembl; ENSPMET00000020933.1; ENSPMEP00000013258.1; ENSPMEG00000015561.1.
DR   Proteomes; UP000261480; Unplaced.
DR   CDD; cd19941; TIL; 1.
DR   Gene3D; 2.10.25.10; Laminin; 1.
DR   InterPro; IPR036084; Ser_inhib-like_sf.
DR   InterPro; IPR014853; VWF/SSPO/ZAN-like_Cys-rich_dom.
DR   InterPro; IPR001007; VWF_dom.
DR   InterPro; IPR001846; VWF_type-D.
DR   PANTHER; PTHR11339; EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED; 1.
DR   PANTHER; PTHR11339:SF398; MUCIN-2-LIKE-RELATED; 1.
DR   Pfam; PF08742; C8; 1.
DR   Pfam; PF00094; VWD; 1.
DR   SMART; SM00832; C8; 1.
DR   SMART; SM00214; VWC; 2.
DR   SMART; SM00216; VWD; 1.
DR   SUPFAM; SSF57567; Serine protease inhibitors; 1.
DR   PROSITE; PS01208; VWFC_1; 1.
DR   PROSITE; PS50184; VWFC_2; 1.
DR   PROSITE; PS51233; VWFD; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          107..285
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
FT   DOMAIN          427..493
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   575 AA;  62259 MW;  E2E0B62B0CB0CD44 CRC64;
     MSSTTARSST SLLSSTAKPP TSSSGVLTTV TTLASAATLE CSDVYPPRQN GESWNTNNCT
     TSTCIEGKVT VIATVCPNVT LPICTNWRKP VKIYEQNGCC LHYECECVCN VWSGSNYMTF
     DGKMYNFQQN CSYYLVKEII SKYNLTITRS NNCDPSDSTF CPLALSVTYQ SVKAVLTQVK
     TSGTPTNVVY VNQKRVYPAY KNSVMLLYGT DMEITALIQD INTKIVYRGS SFSIDLPYSL
     FGGNTEGQCG TCDNSQANDC RSPNGQIESC SESAGLWTLP GTSCVSPSLP SVTATTQPLT
     SSSHLFTPCH SFISPAPFVR SCTYEICNGG NDTCSSLAAY ATECSNAGVC IDWRSDTNGL
     CDHRCPNNKV YMACGPSVEP TCNDRYNRKF QADVTSSANY TQEGCFCPQG TTLFNTVYDT
     CVASCDCVGP DGRPKQPGET WTSECSNCEC DQDSMSVRCE PVICPEVQKP NCSEPGQQLT
     NTTQGCCTTQ TCGQLCYMIS SCQECYCGLN THPTTKLNVI TCRPVVCHTN CSEVREFTEH
     HSGCCCTHNE SGSGTNQTPT GYHGYIHSVC LSAGV
//