ID A0A3B3XEU7_9TELE Unreviewed; 569 AA.
AC A0A3B3XEU7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=FERM domain-containing protein {ECO:0000259|PROSITE:PS50057};
OS Poecilia mexicana.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae;
OC Poecilia.
OX NCBI_TaxID=48701 {ECO:0000313|Ensembl:ENSPMEP00000013488.1, ECO:0000313|Proteomes:UP000261480};
RN [1] {ECO:0000313|Ensembl:ENSPMEP00000013488.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B3XEU7; -.
DR STRING; 48701.ENSPMEP00000013488; -.
DR Ensembl; ENSPMET00000021261.1; ENSPMEP00000013488.1; ENSPMEG00000015840.1.
DR Proteomes; UP000261480; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd14473; FERM_B-lobe; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF5; FERM DOMAIN-CONTAINING PROTEIN 5; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00935; BAND41.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 500..522
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..293
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 337..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 382..396
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..476
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 569 AA; 64910 MW; F38A248B47FDA98B CRC64;
MLSRLMSSSV RSLDRECNCT VRLLDDSEYT CTIQRDAKGQ YLFDLICHHL NLLEKDYFGI
RYVDPDKQRV NYFWPVLSAQ PPFTMCLRVK FYPPDPAALK EEITRYLVFL QVKRDLYHGR
LLCKTSDAAL LAAYILQAEI GDYDPGKHPE GYSSKFQFFP KHSEKLERRI AEIHKTELIG
QTPETSELNF LQKAQTLETY GVDPHPCKDV SGNPAFLAFT PFGFTVLQGN RRVHFLKWEE
VTKLKFEAKT FHIYATQNED RKIILTYFAP TPEACKHLWK CGVENQAFYK LEKSSQVRTV
SSSNLFFKGS RFRYSGKVAK EVMEQSARIK RDPPEIHRAG MVPSRSCPSI THGPRLTSVP
RTRRRAVHIS IMEGLESLRD SAHSTPVRSV SHGDSFMSSR GHLEDGSEAS TSGVISDETY
SPSDSVLPTP VAEDGVELPS ARHLNGAPCS IDEEKESEAR ALKEGRGGEF RPGRKAPRTV
RSRPSQGADV EDLNKFVLSV LRLFLVTIGL LFALLLLLIM LTESDLDIAF LRDIRKTPEF
QQFHFEYFCP LRRWFACKLR WMGGFLVSK
//
